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Found 49 ne-neurology trials

A listing of ne-neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Phase 2 Randomized Blinded study of Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for the treatment of Chronic Aphasia
18 years - 80 years
All genders
Phase 2
The Laboratory for Cognition and Neural Stimulation (LCNS) is currently recruiting individuals who have suffered from stroke and are now experiencing aphasia, a loss or impairment of language abilities, for a clinical trial. The purpose of this study is to determine if Transcranial Magnetic Stimulation (TMS), a form of non-invasive …
 CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18 years - 99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
 Chemotherapy Induced Peripheral Neuropathy Natural History Study (EPIPHANY)
18 years - 99 years
Female
Observational
This is a prospective natural history study of CIPN in approximately 200 participants receiving taxanes (paclitaxel, docetaxel) for breast cancer or vincristine for lymphoma. Participants will be enrolled over approximately 1-year.The purpose of this present study is to prospectively collect clinical and biomarker data from patients receiving neurotoxic chemotherapy who …
 PBFT02-001- Phase 1B Study to Assess a Single Dose of PBFT02 Delivered into Adult Subjects with Fronto-Temporal Dementia (FTD) and Mutations in the Progranulin Gene (GRN)
35 years - 75 years
All genders
Phase 1
This research is being done to study a new way to treat FTD in patients who have the GRN mutation. This process is called “gene therapy”. Gene therapy is an experimental technique that aims to replace the gene that is not working properly with a version of the gene that …
 TEGSEDI Administration in Patients with Polyneuropathy of Hereditary Transthyretin-mediated Amyloidosis (hATTR-PN)
18 years - 99 years
All genders
Phase 4
TEGSEDI (also known as inotersen) is a medicine that has been approved in the United States, Europe and Canada to treat polyneuropathy (nerve damage) caused by hereditary transthyretin amyloidosis (hATTR-PN) in adults. hATTR-PN is a rare genetic disease that worsens over time if left untreated. This research study will examine …
 TEGSEDI study
18 years - 99 years
All genders
Phase 4
This research study is being done at the request of the US Food & Drug Administration (FDA) to collect additional safety information for the commercially available drug TEGSEDI. This research study is being conducted to examine any changes in health or side effects occurring within 24 hours following treatment with …
 An Extension Trial of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures
18 years - 99 years
All genders
Interventional
Open label extension trial of CVL-865 in adults with drug-resistant focal onset seizures to learn how well the investigational drug works and how safe it is for long-term epilepsy treatment. Participants will answer questions; undergo physical-neuro exams; vitals; ECG collection; blood draws; urine collection; questions about the study drug; and …
 A Phase 2a Study of TPN-101 in Patients with Progressive Supranuclear Palsy
41 years - 86 years
All genders
Phase 2
Normal 0 false false false EN-US X-NONE X-NONE The research study is being conducted to assess the safety and tolerability of TPN-101 compared to placebo for the treatment of PSP. The study requires the participant and a caregiver to be part of the study.  If you agree to join the …
18 years - 100 years
All genders
Phase 4
You are being invited to participate in a research study because you have been diagnosed with Parkinson’s disease (PD) and you underwent or have been offered a procedure called Deep Brain Stimulation (DBS) as a treatment option to manage some of your symptoms of Parkinson’s disease. The purpose of this …
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