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Found 49 ne-neurology trials

A listing of ne-neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Evaluate a Next Generation Portable Diagnostic Platform for Determination of Emergency Large Vessel Stroke
22 years - 99 years
All genders
Phase 2
Observational
The purpose of this study is to collect robust cerebral blood flow velocity (CBFV) data collected by transcranial Doppler ultrasound (TCD) to validate the Occlusion Index (OI) as a diagnostic algorithm tool to aid in clinical decision making for large vessel occlusion
 Using Behavioral Economics to Improve Mobility for Adults with Stroke
18 years - 99 years
All genders
Observational
The overall objective of this study is to evaluate the feasibility of a connected health mobility intervention for community-dwelling adults with stroke. We will examine the outcomes of an 8 week mobility intervention on steps per day. Additionally, we will explore individual phenotypes as they relate to intervention responsiveness, which …
 For persons with drug-resistant focal onset seizures, a type of Epilepsy, the study of of cvl-865 as adjunctive therapy.
18 years - 99 years
All genders
Phase 2
Interventional
Trial of CVL-865 as Adjunctive Therapy in Adults With Drug-Resistant Focal Onset Seizures
 Trial-Ready Cohort for the Prevention of Alzheimer's Dementia
50 years - 85 years
All genders
Observational
The purpose of this study is to develop a large, biomarker-confirmed, trial-ready cohort to facilitate rapid enrollment into AD prevention trials. Will utilize feeder registries as well as participants with known biomarker status. Enrollment into TRC involves in-clinic evaluation and biomarker confirmation, with additional visits every 6 months. This may …
 A Study of TAK-071 in People With Parkinson Disease
40 years - 85 years
All genders
Phase 2
Interventional
It is hoped that TAK-071 will help people with Parkinson's disease to walk with better balance. The main aim of the study is to check if there is a difference in how participants walk after treatment with TAK-071. Another aim is to see if it improves how participants think and …
 HELIOS- A:A Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
18 years - 85 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the efficacy and safety of vutrisiran (ALN-TTRSC02) in patients with hereditary transthyretin amyloidosis (hATTR amyloidosis). Participants will receive vutrisiran or the reference comparator patisiran during the Treatment Period.
 A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy ( (ADHERE)
18 years - 99 years
All genders
Phase 2
Study to evaluate the safety and efficacy of the subcutaneous formulation of efgartigimod in adults with CIDP.
 Fixed-Dose Trial in Early Parkinson's Disease (PD) (TEMPO-1)
40 years - 80 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease
 Upregulating action semantics to facilitate naming in aphasia
18 years - 99 years
All genders
Phase 1
The goal of this research is to improve the likelihood of aphasia treatment success by activating brain networks that can compensate for language impairment. We will use non-invasive brain stimulation and gesture-priming paradigms to encourage activation of action knowledge (semantics), which we predict will in turn boost verb retrieval. We …
 Sleep SMART: Sleep for Stroke Management And Recovery Trial
18 years - 99 years
All genders
Observational
The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and improves stroke outcomes at 3 months …
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