A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
An Open-Label, Multicenter, First-in-Human, Dose-Escalation Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas.
Improving the quality of evidence-based interventions (EBIs) for pediatric obsessive-compulsive disorder (OCD) and anxiety disorders for underserved youth is a critical step in reducing mental health care inequities. Youth of color and low-income youth have been impacted by systemic and structural inequities (e.g., racism and discrimination, lack of access to …
The research study is being conducted to develop a test to predict a common complication after lung transplant called primary graft dysfunction (PGD). Predicting PGD before using donor organs may help reduce deaths and improve outcomes of patients receiving a lung transplant in the future.
The research study is being conducted to better understand how fat and muscle are related to disability and health-related quality of life in people with idiopathic pulmonary fibrosis.
The main purpose of the study is to explore the effect of crizanlizumab on kidney function in people with long-term kidney disease caused by SCD. Kidney function of patients who receive crizanlizumab in addition to any regularly prescribed medications will be compared to that of patients who receive their regularly …
People who have had surgery to implant a medical device that helps their heart may have had their surgery done in slightly different ways. In this study, the investigators are looking for people to participate who need to undergo another surgical procedure to change or revise their implanted heart device. …
The first purpose of this study is to test the safety of the addition of a drug called inotuzumab to the usual chemotherapy drugs used for adolescent young adults (ages 18-39). Inotuzumab is investigational and is not FDA-approved. Additionally,this study is to compare any good and bad effects of using …
The study design is a prospective, multicenter, single-arm, global IDE study to evaluate the safety and effectiveness of the Shockwave Medical Coronary Intravascular Lithotripsy (IVL) System in de novo, calcified, stenotic coronary arteries prior to stenting. Disrupt CAD III is being conducted as a staged pivotal study.
This research study is being done at the request of the US Food & Drug Administration (FDA) to collect additional safety information for the commercially available drug TEGSEDI. This research study is being conducted to examine any changes in health or side effects occurring within 24 hours following treatment with …