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Found 1216 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Randomized   Study of Amcenestrant (SAR439859) Plus Palbociclib Versus Letrozole Plus Palbociclib for the Treatment of Patients With ER (+)  HER2 (-) Breast Cancer
18 years - 99 years
All genders
Phase 3
Interventional
The purpose of the study is to evaluate whether SAR439859 (an experimental hormonal treatment), in combination with palbociclib is a better option compared to letrozole (a standard hormonal treatment), in combination with palbociclib, in terms of efficacy and tolerance for treating patients with ER (+), HER2 (-) breast cancer. Eligible …
 Destination Therapy Post Approval Study Product Surveillance Registry Platform Addendum and Apogee
99 years or below
All genders
The purpose of DT PAS PSR is to -Provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products for their intended use -To further confirm safety and effectiveness of the HVAD System when used as intended for DT, in real-world clinical practice The purpose of Apogee …
 Myeloid derived suppressor cell expression in newborn infants: an observational cohort study
1 years - 1 years
All genders
This research study is being conducted to study a type of white blood cells called MDSC in newborn babies. These cells help regulate our body’s immune system. Learning more about these cells may help us to better understand immune function in newborn babies.
 PRESTA- Promoting Recovery after Stroke with Amantadine
18 years - 99 years
All genders
Phase 2
The research team aims to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial. We will randomize patients post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine. Patients will be on study drug or placebo for 1 month but will …
 FS-CAMP: Fed-State Cardiac Arteriovenous Metabolomic Profiling
18 years - 99 years
All genders
This study will enroll subjects who are coming in for a clinical EP procedure that involves the use of venous, coronary sinus, and arterial line placement. Our patient population is primarily from the surrounding urban and suburban region of Penn Medicine.  The research team plans to quantify cardiac metabolism during …
 Analyses of Complement and Other Candidate Fluid Biomarkers in Schizophrenia Spectrum Disorders
18 years - 50 years
Accepts healthy volunteer
All genders
The purpose of this research study is to identify biological markers for schizophrenia and related mental illnesses. We are gathering medical information, behavioral assessments, cells and genetic material (DNA), as well as blood and cerebrospinal fluid (CSF), and brain images from persons who appear to have a psychiatric disorder and …
99 years or below
All genders
The HeartMate 3 requires medicines to keep your blood from clotting knowing as “blood thinners” which can both be anticoagulants and antiplatelet drugs. The standard drugs given when you have the HeartMate 3 are warfarin and aspirin. This study is investigating whether the combination of these drugs as compared to …
 A Randomized  Open Label Pilot Trial of a Biomarker Guided Strategy of Cardioprotection in Patients with Lymphoma or Breast Cancer Treated with Anthracyclines
18 years - 99 years
All genders
Phase 1
You will be receiving anthracycline-based chemotherapy (Adriamycin/doxorubicin) as part of your cancer treatment plan. Although anthracycline-based chemotherapy is effective in treating cancer, it can damage your heart. This study has two goals. The first goal is to see if we can identify who is most at risk for this heart …
 A Study of CDK-002 (exoSTING) in Subjects with Advanced/Metastatic  Recurrent  Injectable Solid Tumors  with Emphasis on Squamous Cell Carcinoma of the Head and Neck  Triple Negative Breast Cancer  Anaplastic Thyroid Carcinoma  and Cutaneous Squamous Cell Carcinoma
18 years - 99 years
All genders
Phase 1
Interventional
Consider this study if you have cancer that is considered advanced and/or has spread to other parts of your body. You have received treatment for your cancer but your cancer has come back or has worsened following that treatment. As part of this study, you will complete routine procedures that …
 Phase I Trial of Programmed Allogeneic CRISPR-edited T cells (PACE) Gene Edited to Eliminate Endogenous TCR  HLA-class I and HLA-class II and Engineered to Express anti-CD19 Chimeric Antigen Receptor (PACE CART19) in Patients with Relapsed Or Refractory CD19+ Leukemia and Lymphoma
18 years - 99 years
All genders
Phase 1
Interventional
This research study is being conducted to evaluate an experimental drug called PACE CART19 in patients with leukemia or lymphoma. PACE CART19 consists of cells from a healthy donor that are genetically modified and designed to target your cancer.
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