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Found 1216 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 APPRAISE Study- Assessment of Primary Prevention Patients Receiving An ICD
21 years - 99 years
All genders
The value of Antitachycardia Pacing (ATP) in primary prevention patients who receive implantable cardioverter defibrilator (ICDs) is uncertain. The purpose of this study is to better understand the value of ATP in primary prevention patients. This study is to see if certain programing will reduce the number of shocks received …
18 years - 99 years
All genders
Phase 2
Please refer to Section 2 of the full protocol (Study Objectives). Please refer to Section 8.1 of the full protocol (Study Endpoints). Please refer to Section 8.1 of the full protocol (Study Endpoints).
 LODESTAR: Study of Rucaparib as Treatment for SoliD Tumors Associated with DEleteriouS MuTations in Homologous RecombinAtion Repair Genes
18 years - 99 years
All genders
Phase 2
This is a Phase 2 multicenter, open-label study evaluating rucaparib as treatment for solid tumors associated with a deleterious mutation in Homologous Recombination Repair (HRR) genes. All patients will be required to have received prior treatment with at least 1 line of life-extending therapy (if available) or have a tumor …
 Study of Daratumumab with Dose-Adjusted EPOCH in Newly Diagnosed Plasmablastic Lymphoma
18 years - 99 years
All genders
Patients with plasmablastic lymphoma are potential participants of this research trial. Patients with a type of B-cell non-Hodgkin lymphoma (NHL) will be invited from Penn Medicine practices. This research study is designed to test the safety of daratumumab, a drug added to the standard lymphoma treatment when given to individuals …
 A Phase 2b Study to Assess the Efficacy  Safety  and Tolerability of Vupanorsen (PF-07285557) in Statin-Treated Participants with Dyslipidemia
40 years - 99 years
All genders
Phase 2
Phase 2b, double-blind, placebo-controlled, parallel group study to provide data on efficacy, safety, tolerability and PK of vupanorsen administered subcutaneously at various doses and regimens with patients with dyslipidemia. Patients will participate for approximately 10 months, and will have blood draws, physical exams, ECGs, and MRIs.
 ARISE - Study to Validate Patient-Reported Outcome Instruments in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18 years - 99 years
All genders
Phase 3
The purpose is to validate patient-reported outcomes questionnaire subjects given ALIS (amikacin liposome inhalation suspension) as part of a study treatment regimen for NontuberculousMycobacterial (NTM) Lung Infection. It will also evaluate the safety and efficacy of the study treatments with ALIS, azithromycin, and ethambutol. Targeted population is patients newly diagnosed …
 PATH Study: Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia
18 years - 99 years
All genders
This research study is to determine the safety and tolerability of pomalidomide for the treatment of HHT; to determine if pomalidomide treatment improves quality of life in HHT; to determine whether a continued response to pomalidomide is evident 12 weeks after treatment discontinuation; to develop a biorepository for future studies …
 ENCORE - Study to Evaluate Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
18 years - 99 years
All genders
Phase 3
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) study treatment on patient-reported symptoms in subjects newly diagnosed with NTM lung infection caused by MAC who have not started standard treatment. This is an experimental clinical research study, and ALIS is …
 TIME- Text-based intervention to minimize the time burden of routine cancer care
18 years - 99 years
All genders
The research study is being conducted to evaluate and test a text message-based strategy to streamline care. Our text message-based triage would screen patients before they come to the clinic, allowing patients with no side effects and normal bloodwork to get their infusion without having to wait. To ensure this …
 A study to assess the efficacy and safety of nemolizumab (CD14152) in Subjects with Prurigo Nodularis
18 years - 99 years
All genders
Phase 3
Interventional
The research study is being conducted using an investigational drug called nemolizumab as a possible treatment for subjects over the age of 18 diagnosed with prurigo nodularis. Procedures include Physical exam, Medical History, blood and urine tests, Electrocardiogram, study medication administered by injection, electronic diary completion and questionnaires. Optional biopsies …
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