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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 TACE Ax HCQ: Phase IB Study of Hepatic Chemoembolization Plus Axitinib and Hydrochlorquine for Liver-Dominant Metastatic Adenocarcinoma Of The Colon And Rectum
18 years - 99 years
All genders
Phase 1
Interventional
Liver metastases are a leading cause of death among patients with metastatic colorectal cancer. Duration of disease control is short following 2nd-line or later systemic therapy. Liver-directed therapy such as TACE has a higher response rate and improves PFS, but the benefit is still limited. Cancer cells escape ischemic cell …
 A Phase 1 Study of IL-15 Superagonist (N-803) and Broadly Neutralizing Antibodies to Induce HIV-1 Control
18 years - 70 years
All genders
Phase 1
This study will investigate whether N-803, a new experimental drug that stimulates the immune system, is safe and tolerable when given alone and in combination with two new experimental drugs that are antibodies (natural proteins that the body makes in response to an infection) to HIV (the virus that causes …
 TRILOGY
18 years - 65 years
All genders
The target population are patients at Penn Medicine undergoing elective bariatric surgery; and are additionally participating in POW-R study ( Protocol #843280) Patients will be recruited to undergo liver wedge and visceral adipose tissue biopsy and provide blood samples. Liver samples will be processed for RNA, metabolomics, and biochemical and …
 UPCC 12119: An Exploratory Biomarker Study of Metastatic Triple-Negative Breast Cancer Patients Treated with Immune Checkpoint Inhibitors
18 years - 99 years
All genders
Interventional
The purpose of this research is to collect clinical information and research tissue samples (blood, tissue, and stool) from patients receiving standard treatment for metastatic triple-negative breast cancer to help researchers better understand the use of immunotherapy in breast cancer.
 STRIDE Study : The Effects of semaglutide on functional capacity in pith type 2 diabetes and peripheral arterial disease
18 years - 99 years
All genders
Phase 3
This is a 52 week, randomized, double-blind, placebo-controlled trial comparing semaglutide 1 mg versus placebo both added to standard of care and administered once weekly in subjects with Type 2 Diabetes Mellitus with Intermittent Claudication.
 Clinical Trial Readiness for SCA1 and SCA3
18 years - 65 years
All genders
Interventional
The prospective study is to establish the world's largest cohort of premanifest and early-stage SCA1 and SCA3 individuals.
 I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients
18 years - 99 years
All genders
Interventional
A trial to compare different investigational agents for their ability to improve clinical outcomes n severely ill patients with COVID-19 pneumonia.
 A071701 Genomically-Guided Treatment Trial in Brain Metastases
18 years - 99 years
All genders
Interventional
This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK or PI3K. Medications that target these genes such …
 GMCI plus Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC Patients (LuTK02)
18 years - 99 years
All genders
This trial is to evaluate the safety and efficacy of adding GMCI to standard of care in patients with stage III/IV NSCLC that are not responding to a first line immune checkpoint inhibitor (ICI).
 Study of Surufatinib in Combination with Tislelizumab in Subjects With Advanced Solid Tumors
18 years - 99 years
All genders
Phase 1
Interventional
study of surufatinib in combination with tislelizumab will evaluate the safety, and tolerability in patients with advanced solid tumors.
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