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Found 1216 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
Phase 2
This is a multicenter, exploratory, open-label study to explore the efficacy and/or pharmacodynamic effect, PK, safety, and tolerability of mavacamten in approximately 35 ambulatory participants with symptomatic HFpEF and elevated cTnI and/or elevated NT-proBNP as defined in inclusion/exclusion criteria. The study will include an up to 7-week screening period (with …
 CAPRICORN-19
18 years - 99 years
All genders
In this study, the Investigators at the University of Pennsylvania will assess organ-specific biomarker profiles (proteins and metabolites), in order to better understand biologic processes, the interplay between the heart and extracardiac organs, and their role in human disease, with an emphasis on cardiovascular disease. The study will specifically focus …
 Phase I Study of Tasquinimod Alone and in Combination with Standard Therapy for Relapsed or Refractory Myeloma
99 years or below
All genders
Phase 1
The research study is being conducted to understand the effects of tasquinimod, an experimental medication, on patients with myeloma. Eligibile subject have multiple myeloma that has been previously treated and is now in need of additional treatment. Part 1 of this study evaluates tasquinimod alone. Part 2 of this study …
 Vitamin D Receptor Agonist Paricalcitol Plus Gemcitabine and Nab-Paclitaxel in Patients with Metastatic Pancreatic Cancer
18 years - 99 years
All genders
Phase 1
Interventional
This research study consists of a safety run-in phase and a randomized phase 2 study which include subjects with previously-untreated, metastatic pancreatic adenocarcinoma. In the run-in safety study, the safety of adding two formulations (IV or Oral) of paricalcitol to a standard chemotherapy program of gemcitabine and nab-paclitaxel will be …
 Intramolecular Imaging with ICG (PRIME)
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
 CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18 years - 99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
 CCN013C
18 years - 40 years
Accepts healthy volunteer
Female
Phase 2
Some research studies have shown that morning-after pills containing LNG do not work as well in preventing pregnancy for women who weigh more than 80kg (176 pounds) and that doubling the dose of LNG would offer greater protection against pregnancy for these women. This study is being done to test …
 Undiagnosed Diseases Network- Clinical and Genetic Evaluation of Patients with Undiagnosed  Disorders
18 years - 99 years
All genders
We are doing this research study to improve diagnosis and care for people with undiagnosed diseases. We are asking you to take part in this research study because you have an undiagnosed disease. About 8000 people will take part over the entire course of this research study. The NIH is …
 FALCON- TRIAL OF THE EFFICACY AND SAFETY OF BARDOXOLONE METHYL IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
18 years - 70 years
All genders
Phase 3
Autosomal dominant polycystic kidney disease (ADPKD) is a multi-organ disorder that results in clusters of fluid-filled cysts in the kidneys and other organs leading to progressive enlargement and loss of organ function. ADPKD is a genetic disorder caused by mutations in the PKD1 and PKD2 genes, which encode the proteins …
 TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
18 years - 99 years
All genders
Normal 0 false false false EN-US JA X-NONE Patients with thoracoabdominal or pararenal aneurysm disease will be asked to take part in this research study This research study will look at treating thoracoabdominal or pararenal aneurysm disease with a new stent-graft design. The reason we are doing this research study …
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