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Found 1216 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Multiple-Site  Phase 1/2  Safety and Efficacy Trial of a Recombinant Adeno-associated Virus Vector Expressing CNGB3 (rAAV2tYF-PR1.7-hCNGB3) in Patients with Congenital Achromatopsia Caused by Mutations in the CNGB3 Gene
99 years or below
All genders
Phase 2
Achromatopsia is an inherited retinal disorder characterized by markedly reduced visual acuity, nystagmus, photoaversion (intolerance to bright light), a small central scotoma, eccentric viewing, and complete or severe loss of color discrimination. The genetic mutations of the disease can be established in the majority of individuals. Approximately 50% are caused …
99 years or below
All genders
Phase 1
This study recruits participants directly from Penn Medicine clinics, during time of their clinical biopsies. Up to 40 participants with known or suspected primary or metastatic breast cancer who meet eligibility requirements for this study will undergo FTT PET/CT study imaging. Each PET/CT scan will include an injection of up …
 Terlipressin to Treat Hepatorenal syndrome- Acute Kidney Injury (HRS-AKI)
18 years - 99 years
All genders
Phase 3
Refer to they synopsis section of the protocol.
 An Open-Label  Safety and Tolerability Phase 1b Trial of CAN04  A Fully Humanized Anti-IL1RAP Monoclonal Antibody  in Combination with Pembrolizumab in Subjects with Solid Tumors Progressing on PD-1/PD-L1 Inhibitor-Containing Regimens
99 years or below
All genders
Phase 1
This study will consider the safety and effectiveness of a study drug, CAN04, in combination with pembrolizumab, in the treatment of incurable or metastatic non-small-cell lung cancer, head and neck squamous cell carcinoma, urothelial cancer, or malignant melanoma. The study aims to establish a recommended dose of CAN04 in combination …
 HOPE Trial
18 years - 99 years
All genders
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease. The hypothesis is that pain coping skills training will be effective at reducing pain and opioid use, and that buprenorphine …
 ASSESSING THE HIV-1 VIRAL RESERVOIR IN TISSUE SAMPLES
18 years - 99 years
All genders
Normal 0 false false false EN-US X-NONE X-NONE Treating HIV infection with antiretroviral therapy (ART) leads to control of the virus and improvement of the immune system, which is your body natural ability to fight diseases. HIV patients who are well controlled (undetectable HIV by blood tests) still have HIV …
 Gene Transfer for Patients With Sickle Cell Disease Using a Gamma Globin Lentivirus Vector
18 years - 99 years
All genders
Phase 1
This Phase 1/2 study will use a novel therapy, ARU-1801, for Sickle Cell Disease, using gene transfer of recombinant -globin lentivirus (LV) vector. The purpose of this study, which involves research, is to determine whether an experimental procedure called “gene transfer” is safe and effective. If you are interested in …
 A study assessing the efficacy and feasibility of virtual cardiac rehabilitation with remotely monitored exercise (VCR)
18 years - 99 years
All genders
This will be an observational study to investigate the feasibility and efficacy of a home-based, tech enabled, remotely supervised, cardiac rehabilitation (CR) program in qualifying American adults who cannot participate in traditional center based rehab.This study aims to investigate the feasibility and effectiveness of Carda Healths remotely administered cardiac rehab …
 Utility of Parametric Response Mapping In Allograft Monitoring After Lung Transplant
18 years - 99 years
All genders
The purpose is to investigate whether parametric response mapping measurements in healthy lung allografts can be used for early detection, prognostication, and phenotyping of CLAD. The target population is bilateral lung transplant recipients who are 6 months post-transplant or later and CLAD free at any of the study institutions. At …
 Treatment In Thoracic Aortic Aneurysm: Surgery versus Surveillance
18 years - 79 years
All genders
This study aims to compare the outcomes of patients undergoing early surgical intervention for ascending aortic aneurysms to those undergoing aneurysm surveillance. Patients with aneurysm diameters between 5.0 and 5.4 cm will be randomized to receive either medical therapy or elective surgery and will be followed annually for 5 years. …
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