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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Early Feasibility Study of the AccuCinch Ventricular Repair System in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF)

99 years or below
All genders
This is a research study sponsored by Ancora Heart, Inc. that will assess the safety and feasibility of the AccuCinch® Ventricular Repair System. This investigational (experimental) device is designed to treat patients who are experiencing symptoms of heart failure due to a dilated left ventricle (heart chamber that pumps blood).
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UPCC 02619: Adjuvant Nivolumab Or Ipilimumab + Nivolumab Determined By Pathological Response To A Single Dose Of Neoadjvuant Nivolumab

99 years or below
All genders
Phase 2
Subjects with Stage III resectable melanoma will receive adjuvant therapy, nivolumab or ipilimumab plus nivolumab, based on whether a pathologic complete response (CR) or near CR (less than 10% viable tumor cells) is achieved with one dose of nivolumab in the neoadjuvant setting followed by surgery.
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Observational Study of Outcomes after EchoMark and EchoSure-based Free Flap Monitoring

99 years or below
All genders
The purpose of this study is to evaluate the performance of the EchoMark and EchoSure (both FDA approved devices) as an ultrasound-based method of monitoring the viability of free flaps and patency of at-risk vessels. The implant and ultrasound will be used per IFU. The primary purpose of the study …
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Implementing the screen and treat strategy for prevention of cryptococcal disease in Botswana: An efficacy and costing study (study protocol V1.5 16th March 2017)

99 years or below
All genders
Adult HIV prevalence in Botswana is estimated at 25%. In 2013, despite widespread availability of antiretroviral therapy (ART), an estimated one-quarter of patients did not initiate ART until their CD4 count was below 147 cells/microL. The early mortality rate in these individuals is high, and cryptococcal meningitis is a leading …
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A Randomized Controled Trial of Transcutaneous Magnetic Stimulation of the Stellate Ganglion to Treat Ventricular Tachycardia Storm

99 years or below
All genders
Two arm, randomized controlled trial with sham therapy control arm to assess the efficacy of low-frequency trans-cutaneous magnetic stimulation of the autonomic nerves in the neck for patients with ventricular arrhythmia. Twenty two (22) subjects with a high burden of ventricular arrhythmia will be randomized to undergo 60-minutes of low …
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Chronic insomnia and CSF markers of dementia - Phase 2

30 years - 50 years
All genders
The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasing vulnerability to dementia. Longitudinal …
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UPCC 10519 / I5B-MC-Y001: An Open-Label Multi-Center Patient Access Program of Olaratumab for the Treatment of Soft Tissue Sarcoma

99 years or below
All genders
The purpose of this program is to allow patients who, in consultation with their treating physician, feel it is in their best interest to continue to receive olaratumab. Only patients with soft tissue sarcoma who are already being treated with olaratumab may enter this program.
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DEVELOPING ORAL LT3 THERAPY FOR HEART FAILURE (DOT3HF)

99 years or below
All genders
Parallel, Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial The primary objective is to evaluate the safety of oral LT3 in heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) The secondary objective is to evaluate the feasibility and preliminary efficacy outcomes of oral LT3 therapy …
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A Phase III Randomized Placebo-Controlled Study to Examine the Efficacy and Safety of DAS181 for the Treatment of Lower Respiratory Tract Parainfluenza Infection in Immunocompromised Subjects

99 years or below
All genders
Phase 3
This purpose of this study is to see if an investigational inhaled medication is safe and effective for the treatment of parainfluenza virus(PIV) in patients with weakened immune systems. Key eligibility criteria are being diagnosed with PIV having received a solid organ or stem cell transplant at any time in …
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Transcranial Magnetic Stimulation Exploration of Motor Cortex Functional Anatomy

99 years or below
All genders
The purpose of the proposed study is to explore the nature of the codes that are present in the primary motor cortex. All complex actions involves the contraction of multiple muscles, the timing and intensity of which is precisely modulated. The traditional view of this process is that an abstract …
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