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Found 1253 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

HIS-BUNDLE CORRECTIVE PACING IN HEART FAILURE

All genders
The aim is to prospectively evaluate the efficacy and mechanism of benefit of HI-CRT vs. BIV CRT in patients with Right Bundle Brank Block (RBBB). Left Ventricular Ejection Fraction (LVEF) will be assess at 6 months following HIS CRT Vs. BIV CRT implant in Heart Failure patients with RBBB.
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A Phase 2a/b Randomized Double-blind Placebo-controlled Parallel Group Multicenter Clinical Study to Evaluate the Efficacy and Safety of OG-6219 in 3 Dose Levels in Women 18 to 49 Years of Age with Moderate to Severe Endometriosis-related Pain

All genders
A study to investigate efficacy and safety of OG-6219 BID in 3 dose levels compared with Placebo in participants aged 18 to 49 with moderate to severe endometriosis-related pain
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A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I Hormone Sensitive HER2-Negative Oncotype Recurrence Score 18 Breast Cancer (DEBRA* DE-escalation of Breast RAdiation)

All genders
Comparison of endocrine therapy alone (experimental arm) vs breast radiation and endocrine therapy (SOC) in hormone-sensitive, stage 1 breast cancer post lumpectomy. Oncotype Recurrence Score must be less than or equal to 18 in order to participate. The experimental arm will be tested for non-inferiority. HRQOL will be collected with …
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A Prospective Multicenter Single-Arm Staged Study to Evaluate the Plan Title: Safety and Effectiveness of EmbraceTM Hydrogel Embolic For Transcatheter Embolization of Arterial Bleeding in Solid Organs and Peripheral Arteries

All genders
This is a prospective, multicenter, single arm, staged clinical study. The study is designed to assess the safety and effectiveness of Embrace Hydrogel Embolic System when used for transarterial embolization for the treatment of arterial bleeding in solid organs and the peripheral vasculature, documented on suitable radiographic and/or endoscopic imaging …
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Pilot Early Feasibility Study of Safety and Effectiveness of Telemetric Intracranial Pressure Monitoring in Spaceflight Participants Before During and After Commercial Orbital Spaceflight

All genders
The participant (astronaut) will enroll in this study because he/she is scheduled for a spaceflight that puts him at risk for developing SANS. This study will monitor ICP and craniospinal compliance by a Miethke M.scio telemetric ICP device. The astronaut will go through centrifuge testing prior to the spaceflight. UPenn …
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THE COMPARATIVE EFFECTIVENESS OF 7 VERSUS 21 HOME-DELIVERED MEDICALLY TAILORED MEALS TO IMPROVE MALNUTRITION RISK IN MALNOURISHED PATIENTS WITH HEART FAILURE: A RANDOM ORDER CROSSOVER FEEDING TRIAL (MEDIMEALS)

All genders
The objectives of the random order crossover design study are to compare the effectiveness of 7- versus 21- meals/week on the primary outcome of malnutrition risk score and secondary outcomes of unplanned emergency department visits or hospital readmissions and on diet quality. The primary outcome is the malnutrition risk score …
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A Multicenter Randomized Controlled Trial of Surveillance vs. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia

All genders
To compare the effectiveness of two approaches for the management of BE and LGD, endoscopic surveillance and endoscopic eradication therapy (EET), using accepted clinical endpoints of neoplastic progression [high-grade dysplasia (HGD)/mucosal esophageal adenocarcinoma (EAC)/invasive EAC] as determined by a blinded central adjudication committee
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A Phase 3 Open-label Clinical Study of Doravirine/Islatravir (DOR/ISL [100 mg/0.25 mg]) Once Daily for the Treatment of HIV-1 Infection in Participants Who Previously Received DOR/ISL (100 mg/0.75 mg) QD in a Phase 3 Clinical Study

All genders
Phase 3
Section 3 HYPOTHESES, OBJECTIVES, AND ENDPOINTS page 35 in the attached protocol. Section 4 STUDY DESIGN page 36-39 in the attached protocol. Section 4 STUDY DESIGN page 36-39 in the attached protocol.
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Lung Transplant Outcomes Group: Tacrolimus

All genders
Using a pilot cohort, we hope to estimate tac PK parameters and conduct simulation studies to support design of a multicenter study to develop and validate a robust post-lung transplant tac population pharmacokinetic (popPK) model. The primary outcome will be the area under the concentration-time curve (AUC), which will provide …
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A prospective multi-center open label and single arm clinical investigation to evaluate the safety and efficacy of using the Zoom Reperfusion System in thrombectomy procedures to treat acute ischemic stroke patients

All genders
REFER TO PROTOCOL
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