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Found 1229 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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MS is a life-long disease that can clinically manifest at a wide range of ages. Lesions in the white matter of the brain can be found at any age in MS patients. How these lesions may affect functioning of the brain is an area we aim to explore. Although connections …
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SAR443820 is a selective, orally bioavailable, central nervous system (CNS)-penetrant, receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitor. The aim of this Phase 2 study is to determine the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of SAR443820 in treating adult participants with amyotrophic lateral sclerosis (ALS).
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ABBV-CLS-7262 is a prodrug that is converted in vivo to the pharmacologically active parent compound A-1684909. A-1684909 is a central nervous system (CNS)-penetrant, eukaryotic translation initiation factor 2B (eIF2B) activator that attenuates the integrated stress response (ISR), a highly conserved cellular mechanism hypothesized to be important in the pathophysiology of …
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This study is an extension of Study 233AS101, a Phase 1/2/3 study evaluating the benefit/risk of BIIB067. This study will evaluate the long-term safety, tolerability, PK, PD, biomarker effects, and efficacy of BIIB067administered to participants with SOD1-ALS.
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The research study is being conducted to learn about the work of breathing support that an external breathing support device can provide compared to a person’s baseline ability. The research study is sponsored by RightAir Inc, the makers of the device being investigated, the AIR-AD cuirass ventilator. This study is …
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This study investigates a specific health condition to understand more about it and how it affects individuals. The purpose is to gather information that may be helpful for future research and treatments.The study focuses on evaluating the condition and collecting data to gain insights into its characteristics and impact on …
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Participants will be asked to provide biological samples at different time points during your pregnancy and delivery of your baby. These samples may be collected when you are getting other clinical tests done or you may be asked to have your blood drawn utilizing a drive up location or …
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Test Trial - v7.0What is the purpose of this study?This study is a randomized, open label, multicenter Phase II trial to evaluate the efficacy and safety of botensilimab (a novel Fc enhanced Tree depleting anti-CTLA4) and balstilimab (a novel anti-PD1) relative to ipilimumab and nivolumab in treatment naïve patients with …
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