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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Long-term Follow-Up Study to Evaluate the Safety and Efficacy of RGX-314

99 years or below
All genders
This is a prospective, observational study designed to evaluate the long-term safety and efficacy of RGX-314. Eligible participants are those who were previously enrolled in a clinical study in which they received a single subretinal administration of RGX-314 (IRB #827859). Participants will be followed for up to 5 years post-RGX-314 …
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A PHASE IV MULTICENTER OPEN-LABEL STUDY EVALUATING B CELL LEVELS IN INFANTS POTENTIALLY EXPOSED TO OCRELIZUMAB DURING PREGNANCY - THE MINORE STUDY

99 years or below
All genders
This study will evaluate the potential placental transfer of ocrelizumab in women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) [in line with the locally approved indications] whose last dose of ocrelizumab was administered any time from 6 months before the last menstrual period (LMP) through to the first …
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MACI Implantation in the Patella: A Multicenter Experience

99 years or below
All genders
This is a retrospective study funded by Vericel Corporation with the goal of collecting clinical characteristics of patients receiving MACI implantation in the patella as part of their standard clinical care as well as patient reported outcome measures.
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A Double-Blinded Randomized Crossover Trial of Stereoencephalography-Guided Multi-Lead Deep Brain Stimulation for Treatment-Refractory Obsessive Compulsive Disorder (SEEG-Guided DBS for OCD)

99 years or below
All genders
Phase 1
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
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NRG-GY026: A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined With Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab Trastuzumab and Hyaluronidase-zzxf (PHESGO) in HER2 Positive Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma

99 years or below
All genders
This Study tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. We would like to rely on CIRB as the IRB of record for …
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UPCC 03423: A Phase 1b/2a Open-label Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of DISC-0974 in Participants with Myelofibrosis and Anemia

99 years or below
All genders
This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the effects on anemia response in subjects with myelofibrosis and anemia. We would like to rely on Advarra as the IRB of record for this study.
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HIS-BUNDLE CORRECTIVE PACING IN HEART FAILURE

99 years or below
All genders
The aim is to prospectively evaluate the efficacy and mechanism of benefit of HI-CRT vs. BIV CRT in patients with Right Bundle Brank Block (RBBB). Left Ventricular Ejection Fraction (LVEF) will be assess at 6 months following HIS CRT Vs. BIV CRT implant in Heart Failure patients with RBBB.
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A Phase 2a/b Randomized Double-blind Placebo-controlled Parallel Group Multicenter Clinical Study to Evaluate the Efficacy and Safety of OG-6219 in 3 Dose Levels in Women 18 to 49 Years of Age with Moderate to Severe Endometriosis-related Pain

99 years or below
All genders
A study to investigate efficacy and safety of OG-6219 BID in 3 dose levels compared with Placebo in participants aged 18 to 49 with moderate to severe endometriosis-related pain
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A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I Hormone Sensitive HER2-Negative Oncotype Recurrence Score 18 Breast Cancer (DEBRA* DE-escalation of Breast RAdiation)

99 years or below
All genders
Comparison of endocrine therapy alone (experimental arm) vs breast radiation and endocrine therapy (SOC) in hormone-sensitive, stage 1 breast cancer post lumpectomy. Oncotype Recurrence Score must be less than or equal to 18 in order to participate. The experimental arm will be tested for non-inferiority. HRQOL will be collected with …
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A Prospective Multicenter Single-Arm Staged Study to Evaluate the Plan Title: Safety and Effectiveness of EmbraceTM Hydrogel Embolic For Transcatheter Embolization of Arterial Bleeding in Solid Organs and Peripheral Arteries

99 years or below
All genders
This is a prospective, multicenter, single arm, staged clinical study. The study is designed to assess the safety and effectiveness of Embrace Hydrogel Embolic System when used for transarterial embolization for the treatment of arterial bleeding in solid organs and the peripheral vasculature, documented on suitable radiographic and/or endoscopic imaging …
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