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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Verification of Risk Assignment for Whole Chromosome Aneuploidy using SNP-based NIPT in VaniSHing Twin Pregnancies

99 years or below
All genders
The main objective of this study is to collect clinical data and blood samples from women with either ultrasound-documented vanishing twin pregnancy or whose Panorama test results suggest increased risk for vanishing twin, and cheek swab samples on their newborn baby to improve the ability of Nateras Panorama (cell free …
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UPCC 04223: Brightline-2: A Phase IIa/IIb open-label single-arm multi-centre trial of BI 907828 for treatment of patients with locally advanced / metastatic MDM2 amplified TP53 wild-type biliary tract adenocarcinoma pancreatic ductal adenocarcinoma or other selected solid tumours

99 years or below
All genders
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder for whom previous treatment was not successful or no treatment exists, to find out whether a medicine called BI 907828 helps. BI 907828 is a so-called MDM2 inhibitor that is being developed to …
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A5394: Safety Tolerability and Impact of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants with Both Chronic Hepatitis B and HIV

99 years or below
All genders
A5394 is a phase II, randomized, double-blind, placebo-controlled clinical trial to assess the safety, tolerability, and efficacy of 24 weeks of treatment with Selgantolimod (SLGN). Intensive PK sampling will be conducted in the first 12 participants who enroll into the study.
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Predicting Epilepsy Surgery Outcomes Using Neural Network Architecture

18 years - 65 years
All genders
The purpose of this study is to test, in surgery patients and controls aged 18 to 65, whether measurable abnormalities found in pre-surgical MRI can predict surgical outcomes in epilepsy, to improve the understanding for the causes of surgical failure, and to pave the way for future use of neuroimaging …
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Improving Sleep in the Neurology In-Patient Population

18 years - 99 years
All genders
The research is being conducted to improve sleep in the inpatient neurology population by decreasing overnight interruptions and addressing environmental barriers to sleep in the hospital. If you agree to join this study, you will be asked to complete the following research procedures: wear an activity and sleep monitor (FitBit), …
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Remote Blood Biomarker Monitoring in Frontotemporal Lobar Degeneration: Neurofilament Survillance Project (NSP)

18 years - 85 years
All genders
This is a biomarker study designed to collect and analyze blood specimens from individuals carrying known familial frontotemporal lobar degeneration (f-FTLD) mutations compared to a control group of individuals without known f-FTLD mutations.
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Study to Investigate Oral Brepocitinib in Adults with Dermatomyositis

18 years - 75 years
All genders
Phase 3
Interventional
This research study is being done to investigate how safe and effective the investigational drug brepocitinib is for treating dermatomyositis. If you agree to join the study, you will be asked to complete the following research procedures: • signing this informed consent • having reviews of your medical/health history and …
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A Phase 4 Randomized Open Label Multicenter Prospective Comparative Study To Evaluate The

99 years or below
All genders
This is a prospective pilot study in which all eligible subjects will be randomized to treatment in the first phase and those with persistent or recurrent heart failure after Phase 1 therapy, may subsequently qualify to be randomized into Phase 2.
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A Single-blind Phase 2 Multi-center Randomized Study to Assess Safety Tolerability Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients with Hepatorenal Syndrome-Acute Kidney Injury

99 years or below
All genders
A Single-blind, Phase 2, Multi-center, Randomized Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients with Hepatorenal Syndrome-Acute Kidney Injury
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A Phase Ib Open-Label Multicenter Study To Investigate The Pharmacokinetics Safety And Tolerability Of Subcutaneous Ocrelizumab Administration In Patients With Multiple Sclerosis

99 years or below
All genders
Requesting a reliance agreement with an external IRB. Study to evaluate pharmacokinetics, safety/tolerability, and immunogenicicty of ocrelizumab admistered subcutaneously in patients with MS. Pre-treated patients will be randomized (1:1) to dose-escalated, subcutaneous or IV administration. Treatment naive patients receive dose-escalated, subcutaneous administration only. All participants may then enter a dose …
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