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Found 1253 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Safety And Therapeutic Measures Of Transcranial Cathodal Direct Current Stimulation (Tdcs) In Patients With Refractory Focal Epilepsy

Safety And Therapeutic Measures Of Transcranial Cathodal Direct Current Stimulation (Tdcs) In Patients With Refractory Focal Epilepsy

9 years - 99 years
All genders
Phase 3
Interventional
The study aims to evaluate the safety, tolerability and efficacy of repeated, daily sessions of transcranial cathodal direct current simulation (tDCS) as administered by the10 STARSTIM (tDCS) device in 10 consecutive days of in-office treatment sessions.
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A Clinical Study to Evaluate the Efficacy and Safety of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

A Clinical Study to Evaluate the Efficacy and Safety of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

18 years - 75 years
All genders
Phase 2
Interventional
The objective for this trial is to determine the effect of GB002 (seralutinib) on improving pulmonary hemodynamics in subjects with World Health Organization (WHO) Group 1 PAH who are Functional Class (FC) II and III.
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Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Stage 2 and 3 Neurotrophic Keratitis Subjects

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Stage 2 and 3 Neurotrophic Keratitis Subjects

18 years - 99 years
All genders
Phase 1
Interventional
The purpose of this study is to compare the safety and effectiveness of the study product, CSB-001 ophthalmic solution 0.1% to placebo when treating stage 2 and 3 Neurotrophic Keratitis.
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AN OPEN-LABEL STUDY OF CK3773274 FOR PATIENTS WITH SYMPTOMATIC HYPERTROPHIC CARDIOMYOPATHY (HCM) AND LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION

All genders
Phase 2
PURPOSE/DESCRIPTION: This is an open label trial to collect long-term safety and tolerability data, including assessments of cardiac structure and function, during chronic dosing with CK3773274. A cardiac magnetic resonance (CMR) imaging sub-study will assess the effects of long-term dosing on cardiac morphology, function and fibrosis.
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CENTRAL VEIN SIGN: A DIAGNOSTIC BIOMARKER IN MULTIPLE SCLEROSIS

All genders
The study is a cross-sectional, multi-center study among subjects with a clinical/radiological suspicion of multiple sclerosis (MS). The study will conduct validation and assess the utility of the central vein sign in MS using magnetic resonance imaging (MRI).
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A Phase 1/2 Ascending Dose Study to Evaluate the Safety and Effects on Progranulin Levels of PR006A in Patients with Fronto-Temporal Dementia with Progranulin Mutations (FTD-GRN)

All genders
Phase 2
Evaluate the safety, tolerability, and immunogenicity of 3 dose levels of PR006A administered via sub-occipital injection into the cisterna magna and Quantify PGRN levels in blood and CSF. Please refer to section 2 of the attached protocol. Please refer to section 2 of the attached protocol.
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UPCC 24420: ULTRA-V: Phase 2 Study to Assess the Efficacy and Safety of Ublituximab in Combination with Umbralisib and Venetoclax (U2-V) in Subjects with Chronic Lymphocytic Leukemia (CLL)

UPCC 24420: ULTRA-V: Phase 2 Study to Assess the Efficacy and Safety of Ublituximab in Combination with Umbralisib and Venetoclax (U2-V) in Subjects with Chronic Lymphocytic Leukemia (CLL)

18 years - 99 years
All genders
Phase 2
This study tests the safety and effectiveness of the combination of ublituximab, umbralisib, and venetoclax. Patients with Chronic Lymphocytic Leukemia (CLL) will be invited to participate in this trial.
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Randomized Double-Blind Placebo-Controlled Proof of Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Traumatic Cervical Spinal Cord Injury

All genders
Phase 2
The objectives of the study are to assess the safety and efficacy of elezanumab in subjects with acute traumatic cervical SCI. The primary endpoint is the Upper Extremity Motor Score (UEMS), a subscore of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI, 2019 criteria) during the treatment …
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Intensive TMS for Rapid Relief of Bipolar Depression Symptoms

Intensive TMS for Rapid Relief of Bipolar Depression Symptoms

18 years - 99 years
All genders
The research study is being conducted to test whether using high dose spaced theta-burst rTMS (a form of transcranial magnetic stimulation) produces a significant reduction in depressive symptoms compared with sham. This project will recruit patients aged 18-70 with symptoms of bipolar depression who have failed (or not shown signs …
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Phase 3 Multicenter Randomized Double-blind Trial of Brexpiprazole as Combination Therapy with Sertraline in the Treatment of Adults with Post-traumatic Stress Disorder

Phase 3 Multicenter Randomized Double-blind Trial of Brexpiprazole as Combination Therapy with Sertraline in the Treatment of Adults with Post-traumatic Stress Disorder

18 years - 65 years
All genders
Phase 3
Patients with post-traumatic stress disorder (PTSD) will be invited to participate in this research study. Participants will be assigned to take one of the following: brexpiprazole, sertraline (also known as “Zoloft”; a marketed antidepressant that has been approved by the United States FDA for the treatment of PTSD), placebo (a …
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