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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Prospective Multicenter Study of Transbronchial Microwave Ablation Using Robotic-Assisted Bronchoscopy in Subjects with Oligometastatic Tumors in the Lung

99 years or below
All genders
The primary objective of the study is to evaluate the safety and effectiveness of the NEUWAVETM FLEX MC Microwave Ablation System and Accessories used in transbronchial ablation procedures for adult subjects with oligometastatic tumors ( 2cm) in the lung. Technique Efficacy: Ablation of the target tumor(s) with the ablation zone …
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UPCC 15522 A Phase 2/3 Study To Evaluate The Efficacy And Safety Of Unesbulin In Unresectable Or Metastatic Relapsed Or Refractory Leiomyosarcoma

99 years or below
All genders
This study will compare the efficacy and safety of unesbulin plus dacarbazine versus placebo plus dacarbazine in participants with unresectable or metastatic, relapsed or refractory LMS who have received at least 1 prior line of systemic therapy.
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Test API load dec 2023

99 years or below
All genders
See protocol section 2 See protocol section 2 See protocol section 2
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Efficacy and Safety of M281 in Adults with Warm Autoimmune Hemolytic Anemia: A Multicenter Randomized Double blind Placebo controlled Study with a Long-term Open-label Extension

99 years or below
All genders
Phase 2
Efficacy of nipocalimab in patients with warm autoimmune hemolytic anemia (wAIHA) Durable response in improvement in hemoglobin (Hgb), defined as attainment of the following at 3 consecutive visits, where at least the first is at or before Week 16, without the need of rescue therapy: 1- Hgb concentration greater than …
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A Prospective and Retrospective Multi-Centre Post-Market Non-Interventional Study of Terumo Aortic* Cardiovascular Patches and Knitted and Woven Graft

99 years or below
All genders
A multicentre, non-interventional, post-market registry to collect safety and performance data on all commercially available knitted and woven grafts, and cardiovascular patches. Data will be collected both retrospectively and prospectively.
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UPCC 09421 Single-Arm Phase 2 Study of Valemetostat Tosylate Monotherapy in Subjects with Relapsed/Refractory Peripheral T-Cell Lymphoma

99 years or below
All genders
This study will characterize the safety and clinical benefit of valemetostat tosylate in participants with relapsed/refractory peripheral T-cell lymphoma, including relapsed/refractory adult T-cell leukemia/lymphoma
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A Phase 2a Randomized Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-5475 in Adults With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease

99 years or below
All genders
This study will assess MK5475 in patients with PH related to COPD. Patients will undergo the following procedures: medical history, lab testing, lung function testing, a CT, EKGs, an echocardiogram, heart catheterization, and 6MWTs.
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Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension

99 years or below
All genders
Determine the reproducibility of the subharmonic aided pressure estimation (SHAPE) algorithm in subjects to estimate portal pressures with an ultrasound scanner. Examine if serial SHAPE can accurately predict development of ascites and other liver related events. Use SHAPE to monitor treatment response in patients identified with portal hypertension and compare …
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Metabolomic Assessment of Frailty in Surgical Patients

99 years or below
All genders
PURPOSE: The overall objective of the project is to perform comparative metabolomics on frail and non-frail patients undergoing major surgery. We hypothesize that frail patients will have distinct baselines, suffer greater metabolic derangements, and recover more slowly than non-frail patients. Additionally, we hypothesize that those patients who undergo prehab will …
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A double-blind randomized placebo-controlled study to assess the safety and efficacy of nebulized PC945 when added to systemic antifungal therapy for the treatment of refractory invasive pulmonary aspergillosis

99 years or below
All genders
This Phase 3, double-blind, randomized, placebo-controlled, parallel-group, multi-center, international study will assess the efficacy, safety and tolerability of nebulized PC945 when added to systemic antifungal therapy for the treatment of refractory invasive pulmonary aspergillosis (IPA).
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