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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Traumatic Brain Injury and Long Term Health: Brain Imaging

Traumatic Brain Injury and Long Term Health: Brain Imaging

55 years - 99 years
All genders
Observational
The overall purpose of this research is to understand the risk factors for Alzheimers disease after Traumatic Brain Injury, including time since diagnosis, ethnicity, and genetic predictors. It is the goal of this multi-center project to disentangle the multiple factors determining individualized brain response to injury and late-life outcomes in …
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HOME for Us- HOME program for individuals with traumatic brain injury and family members

HOME for Us- HOME program for individuals with traumatic brain injury and family members

18 years - 99 years
All genders
Phase 2
Observational
Study of a home based occupational therapy caregiver training program for individuals who have traumatic brain injuries and their family members.
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A study evaluating the safety and efficacy of selective internal radiation therapy (SIRT) using SIR-Spheres® Y-90 resin microspheres on duration of response (DoR) and objective response rate (ORR) in hepatocellular carcinoma (HCC) patients (DOORwaY90 Study)

A study evaluating the safety and efficacy of selective internal radiation therapy (SIRT) using SIR-Spheres® Y-90 resin microspheres on duration of response (DoR) and objective response rate (ORR) in hepatocellular carcinoma (HCC) patients (DOORwaY90 Study)

18 years - 99 years
All genders
Phase 1
Observational
The objective of this pivotal study is to evaluate the safety and effectiveness of SIRT using SIR-Spheres Y-90 resin microspheres as first-line treatment for local control of HCC (Barcelona clinic liver cancer (BCLC) stage A, BCLC stage B1 and BCLC stage B2).
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18F-FluorThanatrace positron emission tomography (PET/CT) in Patients with Metastatic Prostate Cancer

18F-FluorThanatrace positron emission tomography (PET/CT) in Patients with Metastatic Prostate Cancer

18 years - 99 years
Male
Phase 1
Observational
The research study is being conducted to test how a new radioactive imaging drug called 18F-Fluorthanatrace (18F-FTT) can be used to take computerized pictures of places in the body where prostate cancer has spread (metastasized). The pictures will be taken before, and optionally after treatment. 18F-FTT is a drug used …
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INSIGHT: Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

INSIGHT: Investigation of Clot in Ischemic Stroke and Hematoma Evacuation

18 years - 99 years
All genders
Observational
The aim of the study is to collect and analyze specimen from ischemic stroke patients undergoing thrombectomy procedures and from patients undergoing minimally invasive surgery for intracranial hematoma evacuation. Clot and blood specimen will be analyzed via histology, RNA sequencing, Single Nucleotide Polymorphisms (SNPs), and proteomic analysis.
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Open label comparison of injectable buprenorphine (CAM2038 Brixadi ) and naltrexone (Vivitrol ) for opioid use disorder

99 years or below
All genders
Phase 2
Compare brain fMRI response to injectable extended-release buprenorphine (Brixadi, XR-BUP) and naltrexone (XR-NTX, Vivitrol) Our primary outcome combines adherence to treatment and the frequency of illicit opioid use during treatment. The primary outcome is a binary indicator of treatment success: Participants who provide 2 weekly UDS positive for opioids or …
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A Study of REGN5678 (anti-PSMAxCD28) with Cemiplimab (anti-PD-1) in Patients with Metastatic Prostate Cancer

18 years - 99 years
Male
Interventional
This study involves research and is conducted to determine the safety, tolerability (how 6 your body reacts to the drug) and effectiveness of a study drug called REGN5678 which 7 will be given alone first and then be given in combination with cemiplimab.
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A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)

A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)

50 years - 85 years
All genders
Phase 2
Interventional
This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.
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Safety and Efficacy Study of Ravulizumab in Adults With Generalized Myasthenia Gravis

Safety and Efficacy Study of Ravulizumab in Adults With Generalized Myasthenia Gravis

18 years - 99 years
All genders
Phase 3
Interventional
The primary purpose of this study is to evaluate the safety and efficacy of ravulizumab for the treatment of participants with generalized myasthenia gravis (gMG).
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Durvalumab (MEDI4736) with Chemotherapy as First Line Treatment in Advanced Pleural Mesothelioma

Durvalumab (MEDI4736) with Chemotherapy as First Line Treatment in Advanced Pleural Mesothelioma

18 years - 99 years
All genders
Phase 3
Interventional
Patients with malignant pleural mesothelioma (MPM) that cannot be surgically removed will receive first-line treatment with standard chemotherapy of cisplatin or carboplatin and pemetrexed. T Durvalumab is an antibody (a type of human protein) that works by blocking a body substance called Programmed Death-Ligand 1 (PD-L1). Blocking PD-L1 helps the …
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