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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 For persons with drug-resistant focal onset seizures, a type of Epilepsy, the study of of cvl-865 as adjunctive therapy.
18 years - 99 years
All genders
Phase 2
Interventional
Trial of CVL-865 as Adjunctive Therapy in Adults With Drug-Resistant Focal Onset Seizures
 Expanded Access Protocol (Eap) For Subjects Receiving Idecabtagene Vicleucel That Is Nonconforming
18 years - 99 years
All genders
Observational
This study is designed to provide patients access to their nonconforming ide-cel as a treatment option for their disease. The study will evaluate the safety and effectiveness of this therapy through the collection of information. You may or may not receive direct medical benefit from participating in this study. The …
 Study of and Investigational drug  in Participants with Advanced Renal Cell Carcinoma That Has Progressed
18 years - 99 years
All genders
Interventional
The research study is being conducted to evaluate the safety and effectiveness of MK-6482 when compared to treatment with everolimus for renal cell carcinoma.
 A Study to Investigate the Safety and Efficacy of OTL38 Injection for Intraoperative Imaging of Folate Receptor Positive Lung Nodules
18 years - 99 years
All genders
Observational
A study for persons with suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary nodules within the operating theater, and to …
 Trial-Ready Cohort for the Prevention of Alzheimer's Dementia
50 years - 85 years
All genders
Observational
The purpose of this study is to develop a large, biomarker-confirmed, trial-ready cohort to facilitate rapid enrollment into AD prevention trials. Will utilize feeder registries as well as participants with known biomarker status. Enrollment into TRC involves in-clinic evaluation and biomarker confirmation, with additional visits every 6 months. This may …
 A Study of TAK-071 in People With Parkinson Disease
40 years - 85 years
All genders
Phase 2
Interventional
It is hoped that TAK-071 will help people with Parkinson's disease to walk with better balance. The main aim of the study is to check if there is a difference in how participants walk after treatment with TAK-071. Another aim is to see if it improves how participants think and …
 HELIOS- A:A Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
18 years - 85 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the efficacy and safety of vutrisiran (ALN-TTRSC02) in patients with hereditary transthyretin amyloidosis (hATTR amyloidosis). Participants will receive vutrisiran or the reference comparator patisiran during the Treatment Period.
 Study of Durvalumab (MEDI4736) Alone or in Combination With Novel Agents in Subjects With Locally Advanced, Unresectable (Stage III) Non-small Cell Lung Cancer (COAST)
18 years - 99 years
All genders
Phase 2
Interventional
The main purpose of this study is to measure when the effectiveness of durvalumab in combination with other experimental drugs is superior to the effectiveness of durvalumab when used alone. The study is also being done to evaluate the safety and tolerability of durvalumab when used alone and in combination …
 A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy ( (ADHERE)
18 years - 99 years
All genders
Phase 2
Study to evaluate the safety and efficacy of the subcutaneous formulation of efgartigimod in adults with CIDP.
 Vaccine Response in Adults With Atopic Dermatitis (ADopt-VA)
18 years - 55 years
All genders
Phase 3
The research study is being conducted to learn whether an investigational drug called lebrikizumab could impact how effective certain vaccines may be and how effective and safe the study drug is in patients with moderate-to-severe AD compared with placebo. Research procedures include: Physical exam, Medical History, blood and urine tests, …
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