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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluate a Next Generation Portable Diagnostic Platform for Determination of Emergency Large Vessel Stroke

Evaluate a Next Generation Portable Diagnostic Platform for Determination of Emergency Large Vessel Stroke

22 years - 99 years
All genders
Phase 2
Observational
The purpose of this study is to collect robust cerebral blood flow velocity (CBFV) data collected by transcranial Doppler ultrasound (TCD) to validate the Occlusion Index (OI) as a diagnostic algorithm tool to aid in clinical decision making for large vessel occlusion
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Using Behavioral Economics to Improve Mobility for Adults with Stroke

Using Behavioral Economics to Improve Mobility for Adults with Stroke

18 years - 99 years
All genders
Observational
The overall objective of this study is to evaluate the feasibility of a connected health mobility intervention for community-dwelling adults with stroke. We will examine the outcomes of an 8 week mobility intervention on steps per day. Additionally, we will explore individual phenotypes as they relate to intervention responsiveness, which …
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A Randomized Study of Amcenestrant (SAR439859) Plus Palbociclib Versus Letrozole Plus Palbociclib for the Treatment of Patients With ER (+) HER2 (-) Breast Cancer

A Randomized Study of Amcenestrant (SAR439859) Plus Palbociclib Versus Letrozole Plus Palbociclib for the Treatment of Patients With ER (+) HER2 (-) Breast Cancer

18 years - 99 years
All genders
Phase 3
Interventional
The purpose of the study is to evaluate whether SAR439859 (an experimental hormonal treatment), in combination with palbociclib is a better option compared to letrozole (a standard hormonal treatment), in combination with palbociclib, in terms of efficacy and tolerance for treating patients with ER (+), HER2 (-) breast cancer. Eligible …
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FS-CAMP: Fed-State Cardiac Arteriovenous Metabolomic Profiling

FS-CAMP: Fed-State Cardiac Arteriovenous Metabolomic Profiling

18 years - 99 years
All genders
This study will enroll subjects who are coming in for a clinical EP procedure that involves the use of venous, coronary sinus, and arterial line placement. Our patient population is primarily from the surrounding urban and suburban region of Penn Medicine.  The research team plans to quantify cardiac metabolism during …
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A Study to Evaluate the Safety and Tolerability of AB680 Combination Therapy in Participants with Gastrointestinal Malignancies

A Study to Evaluate the Safety and Tolerability of AB680 Combination Therapy in Participants with Gastrointestinal Malignancies

18 years - 99 years
All genders
Phase 1
Interventional
A study to evaluate the safety, tolerability, PK, pharmacodynamics, and clinical activity of AB680 (CD73 inhibitor) in combination with AB122 (programmed cell death-1 inhibitor) and standard chemotherapy (nab-paclitaxel [NP] and gemcitabine [Gem]) in participants with advanced pancreatic cancer.
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Analyses of Complement and Other Candidate Fluid Biomarkers in Schizophrenia Spectrum Disorders

Analyses of Complement and Other Candidate Fluid Biomarkers in Schizophrenia Spectrum Disorders

18 years - 50 years
Accepts healthy volunteer
All genders
The purpose of this research study is to identify biological markers for schizophrenia and related mental illnesses. We are gathering medical information, behavioral assessments, cells and genetic material (DNA), as well as blood and cerebrospinal fluid (CSF), and brain images from persons who appear to have a psychiatric disorder and …
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Antiplatelet Removal and HemocompatIbility Events with the HeartMate 3 Pump

99 years or below
All genders
The HeartMate 3 requires medicines to keep your blood from clotting knowing as “blood thinners” which can both be anticoagulants and antiplatelet drugs. The standard drugs given when you have the HeartMate 3 are warfarin and aspirin. This study is investigating whether the combination of these drugs as compared to …
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A Randomized Open Label Pilot Trial of a Biomarker Guided Strategy of Cardioprotection in Patients with Lymphoma or Breast Cancer Treated with Anthracyclines

A Randomized Open Label Pilot Trial of a Biomarker Guided Strategy of Cardioprotection in Patients with Lymphoma or Breast Cancer Treated with Anthracyclines

18 years - 99 years
All genders
Phase 1
You will be receiving anthracycline-based chemotherapy (Adriamycin/doxorubicin) as part of your cancer treatment plan. Although anthracycline-based chemotherapy is effective in treating cancer, it can damage your heart. This study has two goals. The first goal is to see if we can identify who is most at risk for this heart …
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A Study of CDK-002 (exoSTING) in Subjects with Advanced/Metastatic Recurrent Injectable Solid Tumors with Emphasis on Squamous Cell Carcinoma of the Head and Neck Triple Negative Breast Cancer Anaplastic Thyroid Carcinoma and Cutaneous Squamous Cell Carcinoma

A Study of CDK-002 (exoSTING) in Subjects with Advanced/Metastatic Recurrent Injectable Solid Tumors with Emphasis on Squamous Cell Carcinoma of the Head and Neck Triple Negative Breast Cancer Anaplastic Thyroid Carcinoma and Cutaneous Squamous Cell Carcinoma

18 years - 99 years
All genders
Phase 1
Interventional
Consider this study if you have cancer that is considered advanced and/or has spread to other parts of your body. You have received treatment for your cancer but your cancer has come back or has worsened following that treatment. As part of this study, you will complete routine procedures that …
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A study to establish the diagnostic performance of 18F-fluciclovine positron emission tomography (PET) in detecting recurrent brain metastases after radiation therapy (REVELATE)

18 years - 99 years
All genders
Phase 3
The research study is being conducted to show how effective an imaging drug called 18F-fluciclovine can be used to image uptake before planned surgery. Fluciclovine is a drug used with an imaging test called Positron Emission Tomography/Computed Tomography (PET/CT). PET scan is for detecting suspected recurrence of brain metastases in …
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