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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Accelerating psoriatic arthritis detection in patients with psoriasis
18 years - 99 years
All genders
The study will aim to develop a direct-to-patient screening approach that will improve early psoriatic arthritis (PsA) detection, without burdening dermatologists with PsA screening tasks. We hypothesize that disseminating questionnaires directly to patients outside of a clinic setting will improve early PsA detection, by educating a diverse population of psoriasis …
 A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence
18 years - 99 years
All genders
Phase 3
This is a study in participants with HER2-positive primary breast cancer who have received preoperative chemotherapy and HER2-directed therapy, including trastuzumab followed by surgery, with a finding of residual invasive disease in the breast and/or axillary lymph nodes
 A Study to Evaluate the Effectiveness and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
18 years - 99 years
All genders
Phase 3
Interventional
AL (or light chain) amyloidosis begins in the bone marrow where abnormal proteins misfold and create free light chains that cannot be broken down. These free light chains bind together to form amyloid fibrils that build up in the extracellular space of organs, affecting the kidneys, heart, liver, spleen, nervous …
 A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD ( Graft vs Host)
12 years - 99 years
All genders
Phase 1
This is a multi-center study to evaluate the safety, tolerability, PK, PD, and clinical activity of EQ001 in subjects with Acute Graft Versus Host Disease (aGVHD).
 Maintenance Niraparib and Dostarlimab in Advanced Cholangiocarcinoma
18 years - 99 years
All genders
Phase 2
Interventional
A trial, evaluating molecularly selected, immune-based combination therapy in maintenance treatments for advanced cholangiocarcinoma, selecting patients on the homologous recombination deficient (HRD) signature.
 AcQblate Force Sensing Ablation System US IDE for Atrial Flutter
18 years - 99 years
All genders
Interventional
The objective of the clinical study is to demonstrate the AcQBlate Force Sensing System is safe and effective when used to ablate the cavotricuspid isthmus (CTI) for the treatment of typical atrial flutter .
 A Safety, Pharmacokinetic, Pharmacodynamic and Anti-Tumor Study of PF-06873600 as a Single Agent and in Combination With Endocrine Therapy
18 years - 99 years
Male
Phase 1
Interventional
Open-label, multi-center, non-randomized, multiple dose, safety, tolerability, pharmacokinetic, and pharmacodynamics and clinical activity study of PF-06873600 administered as a single agent and then in combination with endocrine therapy. The study contains two parts, a Part 1 single agent dose escalation and combination endocrine therapy dose finding component and a Part …
 Measurement of B cell maturation antigen-Directed CAR T Cells During TAK-573 Study Participation
1 years - 99 years
Male
Interventional
The primary objective of this pilot study is to explore in a preliminary fashion whether administration of TAK-573 increases the number of BCMA-specific T cells in blood samples from patients with myeloma.
99 years or below
All genders
Phase 2
Compare brain fMRI response to injectable extended-release buprenorphine (Brixadi, XR-BUP) and naltrexone (XR-NTX, Vivitrol) Our primary outcome combines adherence to treatment and the frequency of illicit opioid use during treatment. The primary outcome is a binary indicator of treatment success: Participants who provide 2 weekly UDS positive for opioids or …
18 years - 99 years
Male
Interventional
This study involves research and is conducted to determine the safety, tolerability (how 6 your body reacts to the drug) and effectiveness of a study drug called REGN5678 which 7 will be given alone first and then be given in combination with cemiplimab.
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