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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study to determine safety and tolerability of oral lucerastat in adult subjects with Fabry disease
18 years - 99 years
All genders
Phase 3
The purpose of this study is to study how a new investigational drug called lucerastat works in research subjects. Taking part in a research study is different from getting regular medical care. The aim of regular care is to improve your health. The aim of a research study is to …
 DEFENDO- Study to evaluate safety and efficacy of ophthalmic solution (Oxervate) in patients with Stage 1 Neurotrophic Keratitis (NK)
99 years or below
All genders
This clinical study will be a multi-center, open label, prospective study of 8 weeks of treatment with 24 weeks of follow-up to evaluate the safety and efficacy of OXERVATE 0.002% (20 mcg/mL) cenegermin-bkbj ophthalmic solution administered as one drop in the affected eye(s), 6 times per day at 2-hour intervals, …
 MT-3921- Phase 2  Study to Assess the Efficacy and Safety of MT-3921 in Subjects with Acute Traumatic Cervical Spinal Cord Injury
18 years - 70 years
All genders
Phase 2
MT-3921 is an investigational monoclonal antibody therapy for patients with severe (AIS grade A-C) traumatic cervical spinal cord injury (SCIs). This study aims to compare the efficacy of MT-3921 to a placebo with regard to improving patients sensory and motor function and overall quality of life. Additionally this study aims …
 ConTTRibute: Global Observational Multicenter Long-Term Study of Patients with Transthyretin (TTR)-Mediated Amyloidosis
18 years - 99 years
All genders
Phase 3
This is a prospective global multicenter long-term observational study designed to document the clinical outcomes of patients with hereditary transthyretin-mediated amyloidosis or wild-type transthyretin-mediated amyloidosis and the safety of patisiran (Onpattro) when used in patients with ATTRv amyloidosis. This is data collection study only and no study medication no visits …
 A Phase 2, Umbrella Study With Rolling Arms of Investigational Agents With Either Pembrolizumab in Combination With Chemotherapy or With Pembrolizumab Alone in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
18 years - 99 years
All genders
Interventional
This is an umbrella study designed to learn more about how well different drugs work in non-small cell lung cancer. This study will test MK-4830, MK7-684, and MK-5890 with pembrolizumab and standard chemotherapy or with pembrolizumab alone in subjects with advanced NSCLC.
 Study Evaluating the Efficacy and Safety of AB928-Based Treatment Combinations in Patients with Metastatic Colorectal Cancer
18 years - 99 years
All genders
Phase 1
This study will evaluate the efficacy of investigational drug treatments combinations in patients with metastatic colorectal cancer.
 A Randomized Prospective Evaluation of Four Injectable Neuromodulators in the Glabella Area
30 years - 65 years
Female
Interventional
The overall study object is to quantify the dynamic strain of four commonly available neuromodulators using 3D imaging as well as other potential physical measurements differences over time.
 A Prospective Disease Registry of Patients with Mantle Cell Lymphoma Treated with Novel Agents
18 years - 99 years
All genders
This is an observational study to determine what types of medications patients take to treat MCL as well as how patients respond to those medications.
 A Study to Evaluate the Safety and Tolerability of AB680 Combination Therapy in Participants with Gastrointestinal Malignancies
18 years - 99 years
All genders
Phase 1
Interventional
A study to evaluate the safety, tolerability, PK, pharmacodynamics, and clinical activity of AB680 (CD73 inhibitor) in combination with AB122 (programmed cell death-1 inhibitor) and standard chemotherapy (nab-paclitaxel [NP] and gemcitabine [Gem]) in participants with advanced pancreatic cancer.
 Retreatment with CTL019/CTL119 in Patients with Late Relapse of B-Cell Lymphomas
18 years - 99 years
All genders
Phase 1
Interventional
The primary objective of this study is to evaluate the safety of retreatment of patients with CTL019/CTL119 therapy who have experienced late relapse of lymphoma.
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