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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Sub-study of L-RAD (832203): Collection of Tissue and Fluid Samples for Research in Lymphoproliferative Disorders

99 years or below
All genders
To support the research of lymphoproliferative disorders (LPDs) by supplementing the main repository (IRB #832203) with biospecimens (i.e., tissue and fluid) obtained solely for the purpose of research. These materials will be used for future, unspecified research.
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CAPRICORN-19

CAPRICORN-19

18 years - 99 years
All genders
In this study, the Investigators at the University of Pennsylvania will assess organ-specific biomarker profiles (proteins and metabolites), in order to better understand biologic processes, the interplay between the heart and extracardiac organs, and their role in human disease, with an emphasis on cardiovascular disease. The study will specifically focus …
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CCN013C

CCN013C

18 years - 40 years
Accepts healthy volunteer
Female
Phase 2
Some research studies have shown that morning-after pills containing LNG do not work as well in preventing pregnancy for women who weigh more than 80kg (176 pounds) and that doubling the dose of LNG would offer greater protection against pregnancy for these women. This study is being done to test …
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ONC201 in recurrent high-grade glioma

ONC201 in recurrent high-grade glioma

18 years - 99 years
All genders
Phase 2
This is a phase II, open-label study of ONC201 in adults with recurrent high- grade glioma. Subjects for this study will be recruited from the patient population that present to the Penn Brain tumor center- Department of Neurosurgery or Department of Medicine division of Hematology/ Oncology for evaluation and treatment …
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TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms

TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms

18 years - 99 years
All genders
Normal 0 false false false EN-US JA X-NONE Patients with thoracoabdominal or pararenal aneurysm disease will be asked to take part in this research study This research study will look at treating thoracoabdominal or pararenal aneurysm disease with a new stent-graft design. The reason we are doing this research study …
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A Multi-Center Randomized Double-blind Placebo-controlled Dose-finding Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CK-3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

99 years or below
All genders
Phase 2
Please see section 1 of the full protocol
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MG0003 A Phase 3 Randomized Double-Blind Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

MG0003 A Phase 3 Randomized Double-Blind Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

18 years - 99 years
All genders
Phase 3
This is a Phase 3 study of rozanolixizumab in anti-AChR or anti-MuSK autoantibody-positive patients with generalized MG who experience moderate to severe symptoms and are being considered for treatment with IVIg or PEX. The primary objective of the study is to demonstrate the clinical efficacy of rozanolixizumab in patients with …
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A Phase 3 Multicenter Randomized Double- Blind Placebo- Controlled Study to Evaluate the Efficacy and Safety of AL001 in Individuals at Risk for or With Frontotemporal Dementia Due to Heterozygous Mutations in the Progranulin Gene

99 years or below
All genders
Phase 3
The research study is being conducted to test the safety and tolerability (i.e., possible side effects) of an investigational drug called AL001 and to find out what effects AL001 has on the body. This is for people who have a confirmed progranulin gene mutation that causes frontotemporal dementia (FTD). Study …
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MUSA- Treatment for Mixed Urinary Incontinence: Mid-urethral Sling vs. Botox A

MUSA- Treatment for Mixed Urinary Incontinence: Mid-urethral Sling vs. Botox A

21 years - 99 years
All genders
Interventional
Mixed urinary incontinence (MUI), defined as the presence of both stress urinary incontinence and urgency urinary incontinence, is a challenging condition for which clinicians frequently use multiple sequential treatments that have undergone limited head to head comparison in rigorous clinical trials. Mid-urethral Sling vs. Botox A (MUSA) is a randomized …
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Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized open-label cross-over trial

18 years - 50 years
All genders
Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced -cell mass contributes to the insulin secretory defects that characterizes cystic fibrosis-related diabetes (CFRD), other modifiable determinants appear operative in the emergence and progression of abnormal glucose tolerance towards diabetes. Identifying interventions …
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