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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Randomized  Double-Blind  Placebo-Controlled  Active Comparator Phase 2/3 Study of Tucatinib in Combination With Trastuzumab  Ramucirumab  and Paclitaxel in Subjects With Previously Treated  Locally-Advanced Unresectable or Metastatic HER2+ Gastric or Gastroesophageal Junction Adenocarcinoma (GEC)
19 years - 99 years
All genders
This study is being done to see if tucatinib with trastuzumab, ramucirumab and paclitaxel works better than ramucirumab and paclitaxel to treat HER2-positive (HER2+) cancer of the gut (stomach or gastroesophageal cancer). This study will also look at what side effects happen when participants take this combination of drugs
 Study Of Avb-S6-500 In Combination With Cabozantinib Versus Cabozantinib Alone In Patients With Advanced Clear Cell Renal Cell Carcinoma Who Have Received Front-Line Treatment
18 years - 99 years
All genders
Phase 2
This is a Phase 1b/2 study of AVB-S6-500 designed to evaluate the safety and efficacy of AVB-S6-500 in combination with cabozantinib in subjects with advanced clear cell renal cell carcinoma (ccRCC) that have received front-line treatment.
 A Phase 1/2  Open-Label  First-in-Human Study to Evaluate the Safety and Anti-Tumor  Activity of FS118  a LAG-3/PD-L1 Bispecific Antibody  in Patients with Advanced Malignancies
18 years - 99 years
All genders
This research study is for those with you have advanced cancer. This research study is designed to learn more about the safety and effectiveness of FS118, an investigations drug given to individuals who have been diagnosed with advanced cancer.
 Apneic Oxygenation to Prevent Oxygen Desaturation During Intubation in the NICU: A Randomized Trial
99 years or below
All genders
The objective of this study is to determine whether apneic oxygenation (nasal cannula 6L/min with FiO2 100%) delivered during laryngoscopy and tracheal intubation, compared with no respiratory support or oxygenation during laryngoscopy and tracheal intubation attempts (standard of care), reduces the magnitude of oxygen desaturation during tracheal intubation encounters in …
 A pilot study to determine the feasibility of using plasma to detect mutations in patients with Stage II-III NSCLC
18 years - 99 years
All genders
This study will increase our ability to detect mutations in Stage II-III Non Small Cell Lung Cancer patients.
 INFINITY-Prospective Cohort Study of Mechanistic Associations between Intra-Myocardial Fat Deposition and Ventricular Tachycardia in Ischemic Cardiomyopathy
18 years - 99 years
All genders
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
 Phase I Trial of GFR4 CART Cells in Adult Patients with Recurrent or Metastatic Medullary Thyroid Cancer
18 years - 99 years
All genders
Phase 1
This is an open-label phase 1 study to assess the safety and feasibility of autologous T cells expressing a single-chain scFv targeting GFRa4 with tandem TCR/CD3 and 4-1BB (TCR/4-1BB) costimulatory domains (referred to as CART-GFRa4) in patients with incurable medullary thyroid cancer (MTC). This is a Phase 1 study evaluating …
99 years or below
All genders
PROOF-HD is a placebo-controlled (double blind) multicenter Phase 3 trial of Pridopidine in Huntington Disease patients. Recruitment: 480 participants at 60 sites, a target of 8 participants per site. Procedures include administration of study drug or placebo in tablet form twice daily for a period of 67-80 weeks with option …
99 years or below
All genders
Phase 3
The primary objective is to compare the PFS of patients randomized to MIRV vs. IC Chemo. Secondary objectives include: To compare the ORR of patients randomized to MIRV vs. IC Chemo, to compare OS of patients randomized to MIRV vs. IC Chemo, and to compare the primary patient-reported outcome (PRO) …
18 years - 99 years
All genders
Phase 3
Pleae refer to Section 3 (Objectives and Endpoints) of the full protocol Please refer to Section 3.1 (Primary Endpoint) of the full protocol Please refer to Section 3.2 (Secondary Endpoints) of the full protocol
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