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Found 1253 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Studying imlifidase in comparison to the standard of care in the management of highly sensitized kidney transplant patients.

18 years - 70 years
All genders
Phase 3
Interventional
The purpose of this study is to demonstrate the efficacy and safety of imlifidase in comparison to the standard of care (SoC) in the management of highly sensitized transplant patients.
 Study Evaluating the Safety   and tolerability of AMG 757 and determine the maximum tolerated dose

Study Evaluating the Safety and tolerability of AMG 757 and determine the maximum tolerated dose (DeLLpro-300)

Male
Phase 1
Interventional
To evaluate the safety and tolerability of Tarlatamab and will determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).
 An Extension Study to Assess the Long-Term Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB067 Administered to Previously Treated Adults with Amyotrophic Lateral Sclerosis Caused by Superoxide Dismutase 1 Mutation

An Extension Study to Assess the Long-Term Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB067 Administered to Previously Treated Adults with Amyotrophic Lateral Sclerosis Caused by Superoxide Dismutase 1 Mutation

All genders
Phase 3
Interventional
The primary objective of the study is to evaluate the long-term safety and tolerability of BIIB067 (tofersen) in participants with amyotrophic lateral sclerosis (ALS) and confirmed superoxide dismutase 1 (SOD1) mutation. The secondary objectives are to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), biomarker effects, and efficacy of BIIB067 administered to …

A Randomized, Placebo-controlled, Double-blind, Multicenter Study to Assess the Efficacy and Safety of Nipocalimab in Adults with Primary Sjogren's Syndrome (pSS)

18 years - 75 years
All genders
Phase 2
Interventional
The purpose of this study is to evaluate the efficacy and safety of nipocalimab in participants with primary Sjogren's syndrome (pSS) versus placebo.
 V7.3 Smoke Testing study

V7.3 Smoke Testing study

23 years - 90 years
All genders
This study will be the first of its kind to explore the impact of continuous theta burst stimulation (cTBS) to the intraparietal sulcus (IPS) on arousal symptoms among patients with posttraumatic stress disorder (PTSD). We will demonstrate that IPS cTBS results in significant target engagement in the form of reduction …
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Online study
 World-wide Randomization Antibiotic Envelope Infection Prevention Trial (WRAP-IT)

World-wide Randomization Antibiotic Envelope Infection Prevention Trial (WRAP-IT)

1 years - 100 years
All genders
This study is a single-blinded,randomized,prospective, multi-center clinical trial. The study will evaluate the ability of the TYRX absorable Antibacterial Envelope to reduce major cardiovascular implantable electronic device (CIED) infections. Patients undergoing CIED generator replacement, upgrade, revision or new biventricular defibrillator system will be randomized to receive the TYRX envelope or …

The Neural Basis for Amyotrophic Lateral Sclerosis

18 years - 100 years
All genders
The purpose of this study is to evaluate memory, language and cognitive difficulties in patients with ALS. ALS is a neurological disease that affects nerve cells (motor neurons) in the brain and spinal cord. This condition largely affects the muscles however there are some individuals who also experience other neurological …
 T-Cell Response to Vaccination

T-Cell Response to Vaccination

18 years - 100 years
All genders
The purpose of this study is to see how your body forms a protective response after vaccination and how it deals with viral variants. We are studying the immune response to the COVID-19 vaccines. 

Enteral Nutritional Therapy and the Gut Microbiota and their Metabolites in Ileostomy Contents (EMMI)

18 years - 70 years
All genders
Are you between the ages of 18-70? Do you have an ileostomy? You may be eligible for this study!

“The Shift Worker’s Microbiome”

40 years - 59 years
Male
We are looking for healthy males, age 40-59 years old, non-smoking un-medicated who work the "shift-work" schedule (>3 shifts per month outside 7 am-6 pm for the past 10 or more years & own a smartphone which installs the remote sensing applications. or "day workers" who work 7 am-6 pm …
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