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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

HOPE in Action Prospective Multicenter Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients

99 years or below
All genders
Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …
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A Phase II randomized double-blind study of the use of Rucaparib vs. placebo maintenance therapy in metastatic and recurrent endometrial cancer

99 years or below
All genders
Phase 2
This study plans to learn more about the use of Rucaparib maintenance therapy after completion of prior therapy for recurrent endometrial cancer. Rucaparib belongs to a drug class called PARP inhibitors. There are currently three drugs approved by the U.S. Food and Drug Administration (FDA) in the setting of ovarian …
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A Prospective Observational Study of Outcomes from Proximal Thoracic Aortic Disease

99 years or below
All genders
The purpose of this registry is to collect real-time data for those patients who have aortic disease of their ascending (top) aorta and the aortic arch (curved area where the vessels that supply the brain with blood). The current treatment requires open surgery or a hybrid procedure (open surgery with …
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ALN-AT3SC-003: ATLAS INH: A Phase 3 Study to Evaluate the Efficacy and Safety of Fitusiran in Patients with Hemophilia A or B with Inhibitory Antibodies to Factor VIII or IX

99 years or below
All genders
Phase 3
This study will evaluate the efficacy and safety of fitusiran compared to on-demand treatment with bypassing agents, as determined by the frequency of bleeding episodes in enrolled adult subjects who are who have hemophilia A or B with an inhibitor who are not on prophylaxis.
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A Multicenter Randomized Double-blind Vehicle-controlled Phase 3 Efficacy and Safety Study of Patidegib Topical Gel 2% for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects with Basal Cell Nevus Syndrome

99 years or below
All genders
Phase 3
Subjects 18 years or older diagnosed with basal cell nevus syndrome (BCNS, also known as Gorlin syndrome). The main purpose of this study is to see if the study gel, which is applied to the face, reduces the number of new surgically eligible BCCs and learn more about the safety …
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Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET)

99 years or below
All genders
Phase 1
Adults 65 and older are more likely to have significant injuries from minor things like falls. They can have problems regaining strength due to sarcopenia (loss of muscle tissue as part of natural aging process). Nicotinamide riboside/pterstilbene (Basis) is commercially available nutraceutical. This randomized, double blind placebo controlled trial will …
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The REFLECT Trial: A Randomized Evaluation oF the TriGuard HDH Cerebral Embolic Protection Device and the TriGUARD 3 Cerebral Embolic Protection Device to Reduce the Impact of Cerebral Embolic LEsions after TransCatheter Aortic Valve ImplanTation

99 years or below
All genders
Phase 2
This is a research study designed to look at the safety and effectiveness of the TriGUARD 3 cerebral embolic protection device in patients undergoing transcatheter aortic valve implantation (TAVI). The purpose of the study is to assess whether the TriGUARD 3 can prevent death, stroke, more subtle signs of brain …
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Early Feasibility Study of the AccuCinch Ventricular Repair System in Patients with Heart Failure and Reduced Ejection Fraction (HFrEF)

99 years or below
All genders
This is a research study sponsored by Ancora Heart, Inc. that will assess the safety and feasibility of the AccuCinch® Ventricular Repair System. This investigational (experimental) device is designed to treat patients who are experiencing symptoms of heart failure due to a dilated left ventricle (heart chamber that pumps blood).
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Clinical Performance of the Aptima CMV Quant Assay on the Panther System

99 years or below
All genders
The purpose of this study is to look at the effectiveness of an investigational test called the Aptima CMV Quantification Diagnostic Assay (Aptima CMV Quant Assay) to measure levels of CMV in plasma. The target population is subjects who have tested positive for cytomegalovirus (CMV) after receiving a solid-organ transplant …
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Secondary Distribution of HIV Self-Tests: an Innovative Strategy for Promoting Partner Testing and Reducing Risk

99 years or below
All genders
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