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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Utility of Esophageal Cooling Therapy for the Prevention of Thermal Injury During Atrial Fibrillation Ablation: an investigator initiated randomized blinded single center pilot study

99 years or below
All genders
This is a small scale pilot study to evaluate if esophageal cooling using the Attune Medical Esophageal Heat Transfer Device (EnsoETM) limits the frequency or severity of thermal injury during catheter ablation of atrial fibrillation. This prospective, randomized study will include 40 patients with symptomatic AF undergoing index PVI at …
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Post Approval Study of the remed System

99 years or below
All genders
This Post Approval Study is a multi-center, prospective, open label, single arm cohort study to evaluate the long-term safety, long-term effectiveness, and survival rate in subjects implanted with the remed System from the remed System Pivotal Trial. Up to 94 subjects will be enrolled at up to 21 sites in …
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A Pilot Proof of Concept Single-Center Study of the Use of Oritavancin in Systemic Staphylococcus aureus Infections in Patients with Opioid Use Disorder

99 years or below
All genders
Phase 4
The study participants will be in the study for approximately 2 months including the screening, intervention phase and the 6 weeks of follow-up time
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PERSPIRE: Preventing rehospitalization in lung transplant recipients through mHealth utilizing individualized rehabilitation prescriptions

99 years or below
All genders
Lung transplant recipients have the highest risk of readmission after the index admission among solid organ transplant patients. We hypothesize that targeted, individualized rehabilitation plans will reduce the risk of unplanned readmission in the first year after lung transplantation.To address this hypothesis, we will conduct a prospective cohort study of …
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A Multicenter Randomized Double-Blind Placebo-Controlled 52-Week Maintenance and an Open-Label Extension Study of the Efficacy and Safety of Risankizumab in Subjects with Ulcerative Colitis Who Responded to Induction Treatment in M16-067 or M16-065

99 years or below
All genders
Phase 3
The study will enroll subjects who have completed Study M16-067 or Study M16-065 and have achieved clinical response, defined as decrease from Baseline of induction study of Adapted Mayo score greater than or equal to 2 points and greater than or equal to 30%, PLUS a decrease in rectal bleeding …
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Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)

Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)

18 years - 100 years
All genders
Interventional
The purpose of this study is to find out if a drug called dapagliflozin would be effective in improving the blood tests and symptoms related to your heart failure.
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Management of the Patent Ductus Arteriosus in Premature Infants Trial (PDA Trial)

99 years or below
All genders
Phase 3
This is a pragmatic randomized multicenter, effectiveness study comparing active treatment of a sPDA to expectant management. This trial estimates the risks and benefits of active treatment versus expectant management of a symptomatic patent ductus arteriosus (sPDA) in premature infants.
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Integrated biomarker PET/CT imaging trial for assessing hypoxia in soft tissue sarcomas using a novel PET/CT tracer

Integrated biomarker PET/CT imaging trial for assessing hypoxia in soft tissue sarcomas using a novel PET/CT tracer

99 years or below
All genders
Phase 1
This is a pilot study. Subjects with primary soft tissue sarcoma of the extremities may be eligible for this study. Subjects may participate in this study if they are at least 18 years of age. Most participants will be receiving care at the clinical practices of the University of Pennsylvania …
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A Phase 1/2 Study of Oral LOXO-292 in Patients

99 years or below
All genders
Phase 1
LOXO-292 is a highly potent and specific inhibitor of the RET RTK, with minimal inhibition of other kinase and non-kinase targets, and therefore may be of benefit to patients with tumors (such as NSCLC, MTC, PTC, and colon or breast carcinomas) that harbor RET alterations and/or depend on RET activation. …
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Genomic Epigenetic Proteomic Metabolomic and Immunologic Characterization of Metastatic Neuroendocrine Tumors Surviving Transarterial Embolotherapy

99 years or below
All genders
mNET is commonly treated with TACE or TACE. mNET cells can survive TACE or TARE ischemic conditions. In this study, we will biopsy mNETs being treated with TACE or TARE prior to treatment, after treatment, and again at recurrence to characterize the metabolic, immunologic, and genetic profile of the cells …
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