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Found 66 healthy trials

A listing of healthy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 45 years
All genders
The purpose of this study is to determine if you may be eligible to participate in one of ourcurrent research studies being conducted at the University of Pennsylvania. The purposes ofthese studies are to test different methods that might protect people against viruses thatcause transmittable infections or to develop better …
18 years - 50 years
All genders
Phase 2
The main purpose of this study is to learn if a vaccine that is given as two shots (injections) to prevent spinal meningitis (an infection of the lining of the brain and spinal cord caused by Neisseria meningitidis type B) might also work in preventing gonorrhea (caused by Neisseria gonorrhoeae). …
 T-Cell Response to Vaccination
18 years - 100 years
All genders
This study investigates how the body forms a protective response after receiving a COVID-19 vaccine. The purpose is to understand how the immune system reacts to the vaccine and deals with different viral variants.The study focuses on evaluating the immune response in people who are about to receive a COVID-19 …
 Effects of opioid use disorder and non-fatal overdose on tau pathology; a [18F]PI-2620 PET/CT study
18 years - 60 years
All genders
Phase 2
This study is being conducted to learn more about how opioid use and opioid overdose affects tau levels in the brain. Tau is a protein in the brain that helps stabilize nerve cells structure. We will study tau levels in the brain using a type of Positron Emission Tomography (PET/CT) …
 Metabolomic Reprogramming in insomnia as a Function of Objective Sleep Duration
25 years - 50 years
All genders
The research study is being conducted to understand how insomnia and the amount of sleep people get at night affect metabolism. Four groups of people will be asked to participate: individuals with insomnia who sleep >6 hours per night, individuals with insomnia who sleep <6 hours per night, individuals without …
18 years - 40 years
All genders
Adult healthy volunteers in the age group of 18-40 years, both male and female, and willing to participate in MRI at the University of Pennsylvania, department of  radiology facilitiesMild exercise  with calf muscle  briefly  is required, and MRI will be performed before and after exercise.
16 years - 100 years
Male
Phase 3
The primary objective of the PURPOSE2 study is to evaluate the efficacy of lenacapavir (LEN) in preventing the risk of contracting human immunodeficiency virus (HIV). The study will be conducted in 2 parts: a cross-sectional study (Incidence Phase) and a double-blind, randomized study (Randomized Phase).1) The Incidence Phase will include …
 Pilot Study of a Multi-System Analysis of Opioid Receptor Binding
18 years - 50 years
All genders
This study investigates opioid receptor binding in the brain and body. It aims to understand how these receptors, which are involved in pain reduction and reward experiences, function in different individuals.The study focuses on measuring the binding of a specific type of opioid receptor using a PET/CT scan. This involves …
 COVID-19 Booster Vaccine Immune Responses
18 years - 89 years
All genders
This study aims to understand the antibody response to any COVID-19 booster vaccine in any person eligible and willing to receive a COVID-19 booster. The goal of this study is to ascertain the immunological responses that follow COVID-19 booster vaccines in a wide range of individuals. Our study is offered to …
 FRESCO Study
18 years - 100 years
All genders
This research study is being conducted to compare items in the online Penn Healthy Diet (PHD) survey to data from a 24-hour dietary recall using the online ASA24 Dietary Assessment Tool, and to validate the scoring algorithm developed for the PHD survey. We would also like to find out if metabolites …