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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

UPCC 46420: Phase I Open Label Multicenter Dose Escalation Study of YTB323 in Adult Patients with CLL/SLL and DLBCL

18 years - 99 years
All genders
Phase 1
Please refer to Section 2 of the full protocol (Objectives and endpoints) Please refer to Section 2 of the full protocol (Objectives and endpoints) Please refer to Section 2 of the full protocol (Objectives and endpoints)
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UPCC 26921: A Phase 1a/1b Open-label Dose-Escalation and Expansion Study of TPST-1495 as a Single Agent and in Combination with Pembrolizumab in Subjects with Solid Tumors

99 years or below
All genders
Phase 1
Please refer to Section 4 of the full protocol (Study Objectives and Endpoints) Please refer to Section 4 of the full protocol (Study Objectives and Endpoints) Please refer to Section 4 of the full protocol (Study Objectives and Endpoints)
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UPCC 53418: Tisagenlecleucel versus standard of care in adult patients with relapsed or refractory aggressive B-cell non-Hodgkin lymphoma: A randomized open label phase III trial (BELINDA)

99 years or below
All genders
We would like to rely on the WIRB as IRB of record for this study. The main purpose of this study is to find out if the investigational therapy tisagenlecleucel (i.e. CTL019, CART-19, or Kymriah®) is safe and has beneficial effects in people who have relapsed or refractory aggressive B-cell …
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UPCC 18121: A Phase II Study of NirAparib Dostarlimab and Radiotherapy in Metastatic PD-L1 Negative or Immunotherapy-Refractory Triple-Negative Breast Cancer (NADiR)

99 years or below
All genders
Phase 2
Please refer to Section 4 of the full protocol (Objectives) Please refer to Section 18.4 of the full protocol (Analysis of Primary Endpoints) Please refer to Section 18.5 of the full protocol (Analysis of Secondary and Exploratory Endpoints)
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Financial Hardship among Patients with Acute Respiratory Failure and their Family Member Caregivers: Understanding the Impact on Patient and Family- Centered Outcomes

18 years - 99 years
All genders
Observational
The purpose of this study is to better understand how being in the intensive care unit (ICU) can contribute to patients’ and family caregivers’ financial hardship and cause stress. Our goal is to advance our understanding of factors that contribute to financial hardship. Results from this study will help inform …
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Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinsons Disease

30 years - 80 years
All genders
The LRRK2protein may contribute to disease progression in patients with PD.The study drug (BIIB122) is designed to affect the activity of LRRK2 protein in the brain and may prevent or delay the development of PD symptoms.The main purpose of this study is to look at whether the study drug works …
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Understanding Rare Inflammatory Skin Diseases

18 years - 99 years
All genders
Observational
To understand how rare human inflammatory skin diseases develop and work, we will collect your human tissue from lesional (diseased and affected) and non-lesional (normal, unaffected) skin, as well as blood, cheek swab(s), photographs of the biopsy sites or rash, and medical information.
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Evaluating CART-EGFR-IL13Ra2 Cells Following Lymphodepleting Chemotherapy in Patients With EGFR-Amplified Recurrent Glioblastoma

99 years or below
All genders
Phase 1
This research study is being conducted to evaluate an experimental drug called CART EGFR-IL13Ra2 cells in patients with glioblastoma that has returned or worsened on current treatment.
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CONFOCAL LASER ENDOMICROSCOPY NODULE LOCALIZATION BY ROBOTIC BONCHOSCOPY (CLEAR STUDY)

18 years - 99 years
All genders
Interventional
This research study is being done to investigate if a new technique called ‘needle-based confocal laser endomicroscopy’ (abbreviated as nCLE) is helpful in patients who are undergoing a bronchoscopy to obtain a tissue sample (biopsy) of a lung nodule. The nCLE technique will be used as an addition to the …
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Evaluating Study Drug BIIB059 in Participants with Active Subacute Cutaneous Lupus Erythematosus and/or Chronic Cutaneous Lupus Erythematosus with or without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)

18 years - 99 years
All genders
Phase 2
Interventional
The research study is being conducted to investigate if the study drug BIIB059 can reduce disease activity and inflammation in people with active Cutaneous Lupus Erythematosus compared to a placebo. Participants will complete the following research procedures: demography and medical history, previous CLE therapy, SARS-CoV-2 (COVID-19) test, chest X-ray, skin …
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