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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

ImmuneSense Study- Safety and Efficacy of IGV-001 an Autologus Cell Immunotherapy With Antisense Oligonucleotide (IMV-001) Targeting IGF-1R in Newly Diagnosed Patients With Glioblastoma Multiforme

ImmuneSense Study- Safety and Efficacy of IGV-001 an Autologus Cell Immunotherapy With Antisense Oligonucleotide (IMV-001) Targeting IGF-1R in Newly Diagnosed Patients With Glioblastoma Multiforme

18 years - 99 years
All genders
Phase 2
The purpose of this study is to see how safe the study medicine, IGV-001 plus standard of care (SOC), is and to compare IGV-001 with placebo (only standard of care) to see if it works in slowing GBM tumor regrowth. Participants for this study will be recruited from the patient …
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Improving Clinical Outcomes of Auditory Brainstem Implantation with Speech-Evoked Auditory Brainstem Responses

Improving Clinical Outcomes of Auditory Brainstem Implantation with Speech-Evoked Auditory Brainstem Responses

18 years - 99 years
All genders
The goal of this study is to improve the reliability of acquiring open-set speech recognition following ABI placement for retrocochlear deafness, to evaluate whether state of consciousness influences speech-based ABR. The researchers hypothesize that: 1) It will be possible to elicit speech-based ABR from surgically anesthetized patients. 2) Surgically anesthetized …
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EA2197: Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial

EA2197: Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial

18 years - 99 years
All genders
This phase II/III trial compares the effect of adding chemotherapy before and after surgery versus after surgery alone (usual treatment) in treating patients with stage II-III gallbladder cancer. This study will determine whether giving chemotherapy before surgery increases the length of time before the cancer may return and whether it …
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DECODE Biologic-Describing the Consequences of Delays in Biologic initiation Study

DECODE Biologic-Describing the Consequences of Delays in Biologic initiation Study

18 years - 99 years
All genders
This study plans to learn more about the usage and effect of biologic medications with patients that have inflammatory bowel disease (IBD). IBD includes both Crohn’s Disease (CD) and Ulcerative Colitis (UC), which currently affects around 1.5 million Americans. Medical therapies for IBD focus on reducing the inflammation of the …
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A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma (CARTITUDE-2)

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma (CARTITUDE-2)

18 years - 99 years
All genders
Interventional
The purpose of this study is to see if JNJ-68284528 is safe and useful for treating patients with relapsed or refractory multiple myeloma.
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Study of JNJ-75229414 a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against KLK2 for Metastatic Castration-Resistant Prostate Cancer

Study of JNJ-75229414 a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against KLK2 for Metastatic Castration-Resistant Prostate Cancer

18 years - 99 years
Male
Phase 1
Interventional
The purpose of this study is to determine recommended Phase 2 dose (RP2D) regimen(s) of JNJ-75229414 in Part 1 (Dose Escalation and to determine safety at the RP2D regimen(s) in Part 2 (Dose Expansion).
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The EPIC Study: Epidemiology of Diabetes Interventions and Complications Study

18 years - 99 years
All genders
The EDIC Study is a follow-up study to the Diabetes Control and Complications Trail ( DCCT) conducted between 1983- 1993. The primary aim of the EDIC Study ( for years 2017-2022) is to examine the prevalence of cognitive, affective, and physical impairments in T1DM, and the association of DCCT treatment …
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A Study of Osimertinib with or without Platinum Plus Pemetrexed Chemotherapy as First-line Treatment in Patients with Epidermal Growth Factor Receptor (EGFR) Mutation- Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer

A Study of Osimertinib with or without Platinum Plus Pemetrexed Chemotherapy as First-line Treatment in Patients with Epidermal Growth Factor Receptor (EGFR) Mutation- Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer

18 years - 99 years
All genders
Phase 3
Interventional
The purpose of this study is to try to find out if an experimental combination of an oral medication called osimertinib when used in combination with chemotherapy is more effective than giving osimertinib alone for the treatment of non-small cell lung cancer (NSCLC). Eligible subjects will be adult subjects with …
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Mismatch Prospective Cohort Study (MPC)

18 years - 99 years
All genders
This study will measure the amount of a protein in the brain known as tau using an imaging procedure called Positron Emission Tomography (PET/CT). Findings from this study lead to a better understanding of factors that influence the course of Alzheimer’s and other diseases of aging. Participation in this study …
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58-WEEK OPEN-LABEL TRIAL OF TAVAPADON IN PARKINSONS DISEASE (TEMPO-4 TRIAL)

40 years - 80 years
All genders
Phase 3
Interventional
The research study is being conducted to study of an investigational drug (referred to as “study drug” in this document) called CVL-751 (also known as Tavapadon) as a possible treatment for Parkinson’s disease. An investigational drug is one that has not been approved by the United States (US) Food and …
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