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Found 1253 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Testing novel drugs or drug combinations to treat breast cancer before surgery

Testing novel drugs or drug combinations to treat breast cancer before surgery

18 years - 99 years
Female
A clinical trial to determine whether adding experimental agents to standard neoadjuvant paclitaxel (with or without trastuzumab), anthracycline, nad cyclosphosphamide increases the probability of pathologic complete response (pCR) over standard neoadjuvant chemotherapy for each biomarker signature established at trial entry, and to determine for each experimental agent used, the predictive …
 Single-Patient Expanded Access Protocol for Tradipitant in a Single Patient with Gastroparesis.”

Single-Patient Expanded Access Protocol for Tradipitant in a Single Patient with Gastroparesis.”

18 years - 99 years
All genders
Interventional
This study is not open to participants that have not completed the induction study. This treatment plan is for a single patient with gastroparesis who has requested expanded access to tradipitant. Gastroparesis is a condition where the stomach is unable to perform its normal functions. Individuals with gastroparesis have delayed …
 Tissue Collection for Multiple Myeloma Research

Tissue Collection for Multiple Myeloma Research

18 years - 99 years
All genders
Interventional
The primary purpose of this research study is to obtain specimens (blood, bone marrow, and other tissues) for research about multiple myeloma and related diseases.
 nuMoM2b Heart Health Study 2

nuMoM2b Heart Health Study 2

18 years - 99 years
Female
Phase 2
Interventional
This study is looking at the relationship between experiences during pregnancy and cardiovascular health. The investigators are recruiting women from the approximately 10,000 women who were enrolled and followed over the course of their first pregnancy in another study. This is a follow-up study to the IRB approved protocol 820716.
 A Randomized Study Comparing Venetoclax and Azacitidine to Induction  Chemotherapy for Newly Diagnosed Fit Adults with Acute Myeloid Leukemia

A Randomized Study Comparing Venetoclax and Azacitidine to Induction Chemotherapy for Newly Diagnosed Fit Adults with Acute Myeloid Leukemia

18 years - 99 years
All genders
Phase 2
Interventional
This research is being done to see how an investigational combination of study drugs works in comparison to chemotherapy in people with acute myeloid leukemia. This study involves the following study drug combinations. You will only receive one of these combinations: • Venetoclax and azacitidine (investigational combination) • Cytarabine and …
 Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy

18 years - 99 years
All genders
Phase 3
Interventional
This trial compares nephrectomy (surgery to remove a kidney or part of a kidney) with nivolumab to the usual approach of nephrectomy followed by standard post-operative follow-up and monitoring, in treating patients with kidney cancer that is limited to a certain part of the body (localized). Nivolumab is a drug …
 A Study Using the CIVO Platform to Evaluate Intratumoral Microdoses of Anti-Cancer Therapies in Patients with Solid Tumors

A Study Using the CIVO Platform to Evaluate Intratumoral Microdoses of Anti-Cancer Therapies in Patients with Solid Tumors

18 years - 99 years
All genders
Phase 1
Observational
A study designed to study the localized pharmacodynamics (PD) of anti-cancer therapies within the tumor microenvironment (TME) when administered intratumorally in microdose quantities via the CIVO device in patients with surface accessible solid tumors for which there is a scheduled surgical intervention.
 A Phase 2a Study of TPN-101 in Patients with Progressive Supranuclear Palsy

A Phase 2a Study of TPN-101 in Patients with Progressive Supranuclear Palsy

41 years - 86 years
All genders
Phase 2
Normal 0 false false false EN-US X-NONE X-NONE The research study is being conducted to assess the safety and tolerability of TPN-101 compared to placebo for the treatment of PSP. The study requires the participant and a caregiver to be part of the study.  If you agree to join the …
 PEERLESS Study

PEERLESS Study

All genders
The FlowTriever Retrieval/Aspiration System (referred to as “FlowTriever”) is an FDA-cleared device designed to treat pulmonary embolism (PE). A PE is a blood clot trapped in your lung. The FlowTriever is used to remove the clot by pulling it into a catheter so that the clot can be removed from …
 JAGUAR- ObJective Analysis to GaUge EVAR Outcomes Through Randomization

JAGUAR- ObJective Analysis to GaUge EVAR Outcomes Through Randomization

21 years - 99 years
All genders
Phase 4
This post-approval study will collect safety, performance, effectiveness, and neck dilatation data on Alto Abdominal Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms and evaluate real-world outcomes in comparison to commercially available comparator devices. Penn Medicine patients with the Alto Abdominal Stent Graft System, a device …
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