Found 1216 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a Phase 1/2, multicenter, open label, study of DCC-3116 as monotherapy, and in combination with trametinib, binimetinib, or sotorasib in patients with advanced or metastatic solid tumors with RAS/MAPK pathway mutation. The study consists of 2 parts, a dose-escalation phase, and an expansion phase.
Parkinson’s disease is a chronic disease of the nervous system that gets worse over time. Available treatments cannot stop or slow down the worsening over time. Some evidence suggests that people with Parkinson’s disease may have more inflammation in the brain. This is thought to be one of the reasons …
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. Research has shown that denosumab may also reduce the risk of developing breast cancer in women carrying a BRCA1 germline mutation.
The purpose of this study is to learn if the study drug (Dupixent® Dupilumab) helps to control asthma. We are particularly interested in understanding if people who have a certain genetic make-up (genotype) will respond better to this treatment. Participants will take inhaler (Dulera®mometasone/formoterol) about 2-12 weeks. Total study duration …
The main goal of this study is to look at the safety and effect of a drug called ARGX-117 in people with multifocal motor neuropathy (MMN). Other goals of the study are to collect information about: • How well different doses of ARGX-117 work • How your body removes ARGX-117 …
This research study is being conducted to determine if diet quality and blood glucose levels in women trying to achieve pregnancy are affected by food insecurity and other social stressors If you agree to participate in the study, you will be asked to complete the following research procedures: collection of …
The research study is being conducted to test the long-term safety, tolerability and effectiveness of rozanolixizumab in adult patients with generalized myasthenia gravis (MG) who have already taken part in the MG0003 study and is intended to replace MG0004. This study will evaluate 6-week treatment cycles of rozanolixizumab in study …
The research study is being conducted to determine the safety and effectiveness of an investigational device, the Edwards PASCAL Transcatheter Valve Repair System (hereinafter referred to as the PASCAL System), with optimal medical therapy (OMT) compared to optimal medical therapy alone in the treatment of patients with symptomatic, severe tricuspid …
The study is investigating efficacy, safety and tolerability of DNA-damage Response Agents (or Combinations), in participants with advanced/metastatic solid malignancies whose tumours contain molecular alterations.
The research study is being conducted to test an experimental drug, GS-8588, for the treatment and remission of human immunodeficiency virus (HIV) infection. GS-8588 is a special type of protein, called an antibody, that helps the immune system bring your immune cells closer to the cells infected with HIV. Finding …
