A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical …
The purpose of this study is to compare the effectiveness and implementation of two suicide prevention strategies for autistic youth: the Safety Planning Intervention tailored for Autistic individuals (SPI-A) and SPI-A plus follow-up care (SPI-A+). Participants are 150 clinicians and 1500 autistic youth (ages 15-24) who receive either SPI-A or …
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Eligible participants will be women ages 18+ scheduled for vaginal birth.
The purpose of this study is to study how well patients that receive a kidney from an HIV+ organ donor do over 10 years compared to patients that receive a kidney from an HIV- donor. People 18 years of age and older with end-stage renal disease and HIV, and who …
This study is being done to determine what effects the therapy venetoclax has on acute lymphoblastic leukemia (ALL).This investigational therapy will be added to what is a standard, liposomal vincristine, to treat relapsed ALL.
This study is being done to determine how well the study drug, BGB-290, gets into the brain tumor and to confirm if we can continuously and safely give BGB-290 and temozolomide as a combination treatment after surgery. We are testing a dose of temozolomide once a day combined with the …
This is a Phase 1/2, multicenter, open label, study of DCC-3116 as monotherapy, and in combination with trametinib, binimetinib, or sotorasib in patients with advanced or metastatic solid tumors with RAS/MAPK pathway mutation. The study consists of 2 parts, a dose-escalation phase, and an expansion phase.
Parkinson’s disease is a chronic disease of the nervous system that gets worse over time. Available treatments cannot stop or slow down the worsening over time. Some evidence suggests that people with Parkinson’s disease may have more inflammation in the brain. This is thought to be one of the reasons …
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. Research has shown that denosumab may also reduce the risk of developing breast cancer in women carrying a BRCA1 germline mutation.
The purpose of this study is to learn if the study drug (Dupixent® Dupilumab) helps to control asthma. We are particularly interested in understanding if people who have a certain genetic make-up (genotype) will respond better to this treatment. Participants will take inhaler (Dulera®mometasone/formoterol) about 2-12 weeks. Total study duration …