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Found 1229 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a study to evaluate the efficacy and safety of Belzutifan monotherapy in participants with advanced pheochromocytoma/paraganglioma (PPGL) or pancreatic neuroendocrine tumor (pNET). The primary objective of the study is to evaluate the objective response rate (ORR) of belzutifan per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST …
The purpose of this study is to continue to collect long term information on the safety of pembrolizumab or pembrolizumab-based combinations that you received or are receiving as part of the protocol you are currently enrolled in, to see how well the drug/s work and how your body reacts to …
Preeclampsia is a serious medical condition that can happen during pregnancy. It usually starts with increasing blood pressure and could affect liver, kidney or other organ functions. This study will to assess whether daily treatment with investigational drug pravastatin administered early in pregnancy reduces the rate of preeclampsia in high-risk …
The purpose of this research study is to compare the performance of the investigational (experimental) tricuspid valve repair system plus optimal drug therapy with optimal drug therapy alone. Participants will be randomly assigned to treatment with either the TriClip device (device group) or No TriClip device (control group). Participants will …
The purpose of this study is to determine the safety and tolerability of an experimental medication PLN-74809 to treat primary Sclerosing Cholangitis (PSC), a rare, long-term liver disease affecting the bile ducts (small tubes) inside and outside the liver. Participants will visit the study center 8 times within 22 weeks. …
This study will test danicopan, a new drug that is being developed by Alexion to slow down progression of GA. The goals of this study are as follows: • To find out whether danicopan can slow the rate of GA disease progression, and in turn slow the loss of visual …
The purpose of this study is to test a new drug called AGN-151586 as a treatments for patients with moderate to severe frown lines between the eyebrows (glabellar) over a period of 18 weeks. Procedures include Vital signs, Physical Exam, Medical History, Blood and Urine tests, ECG, Neurological exam and …
This trial compares the addition of nivolumab to chemotherapy (carboplatin and paclitaxel) versus usual treatment (chemotherapy alone) for the treatment of anal cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor …
The purpose of this study is to test letermovir when given to people who have both well-controlled HIV infection and asymptomatic CMV infection. This study will also gather data on the effectiveness of letermovir to reduce inflammation when compared to no anti-CMV study treatment. In addition, the study will collect …
To evaluate an investigational, personalized adjuvanted vaccine, GEN-009, that is being developed for the treatment of patients with solid tumors. A personalized vaccine, consisting of between 4 to 20 synthetic long peptides, will be generated for each patient and shall be administered as an adjuvanted vaccine, with the adjuvant Hiltonol.
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