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Found 1243 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Myeloid derived suppressor cell expression in newborn infants: an observational cohort study

Myeloid derived suppressor cell expression in newborn infants: an observational cohort study

1 years - 1 years
All genders
This research study is being conducted to study a type of white blood cells called MDSC in newborn babies. These cells help regulate our body’s immune system. Learning more about these cells may help us to better understand immune function in newborn babies.
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PROSPECTIVE VALIDATION OF COMPUTER-ASSISTED CARDIAC HISTOLOGIC EVALUATION OF ALLOGRAFT REJECTION

18 years - 80 years
All genders
Observational
To identify clinically evident rejection events with consistency and accuracy using Computer Assisted Cardiac Histologic Evaluation (CACHE) system that surpasses that of the standard ISHLT rejection grading by trained pathologists
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A Prospective Disease Registry of Patients with Mantle Cell Lymphoma Treated with Novel Agents

A Prospective Disease Registry of Patients with Mantle Cell Lymphoma Treated with Novel Agents

18 years - 99 years
All genders
This is an observational study to determine what types of medications patients take to treat MCL as well as how patients respond to those medications.
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PRESTA- Promoting Recovery after Stroke with Amantadine

PRESTA- Promoting Recovery after Stroke with Amantadine

18 years - 99 years
All genders
Phase 2
The research team aims to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial. We will randomize patients post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine. Patients will be on study drug or placebo for 1 month but will …
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Retreatment with CTL019/CTL119 in Patients with Late Relapse of B-Cell Lymphomas

Retreatment with CTL019/CTL119 in Patients with Late Relapse of B-Cell Lymphomas

18 years - 99 years
All genders
Phase 1
Interventional
The primary objective of this study is to evaluate the safety of retreatment of patients with CTL019/CTL119 therapy who have experienced late relapse of lymphoma.
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Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging HIV Infection and Inflammation

Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging HIV Infection and Inflammation

40 years - 99 years
All genders
Interventional
This study will look at the relationships between HIV infection, age and the immune system, and how these relate to the development of non-infectious illnesses such as heart disease, kidney disease, cancer, memory problems, and diabetes. Further, we will look at how demographic factors, behaviors, and social factors like social …
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Brain Arterio-Venous Metabolomic Profiling

Brain Arterio-Venous Metabolomic Profiling

18 years - 99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
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Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC)

Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC)

18 years - 99 years
Female
Phase 2
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
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Study to Evaluate the Safety Tolerability and Preliminary Efficacy of XmAb 20717 Alone or in Combination with Chemotherapy or Targeted Therapies in Selected Subjects with Metastatic Castration-Resistant Prostate Cancer

Study to Evaluate the Safety Tolerability and Preliminary Efficacy of XmAb 20717 Alone or in Combination with Chemotherapy or Targeted Therapies in Selected Subjects with Metastatic Castration-Resistant Prostate Cancer

18 years - 99 years
All genders
The primary purposes of this research study are to determine the safety and tolerability of XmAb20717 by itself and in combination with other anticancer therapies. Subjects are being asked to take part in this research study because they have metastatic castration resistant prostate cancer (mCRPC), a prostate cancer that has …
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Bupivacaine RCT- Bupivacaine as Adjuvant for Post-operative Pain in Mohs micrographic surgery

Bupivacaine RCT- Bupivacaine as Adjuvant for Post-operative Pain in Mohs micrographic surgery

18 years - 99 years
All genders
The research study is being conducted to find the best ways to reduce pain after Mohs surgery. The research team hopes to learn if adding additional numbing medication at the end of surgery will help reduce pain afterwards. Penn Medicine patients having Mohs surgery will be invited to participate in …
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