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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Effect of Dapagliflozin on Submaximal Exercise Tolerance in Heart Failure

18 years - 99 years
All genders
The primary purpose of this study is to test whether the dapagliflozin (Dapa) will improve exercise duration in people with Heart Failure (HF). In HF, patients are limited in their ability to do all the things they want to do, and exercise as much as they would like, due to …
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Study to evaluate SAF312 eye drops in the treatment of post-operative corneal induced chronic pain (CICP) following Photorefractive Keratectomy (PRK) or Laser-assisted in Situ Keratomileusis (LASIK) surgeries

99 years or below
All genders
Many patients suffer from acute ocular pain due to different problems, however there is no available treatment for chronic eye pain (long lasting eye pain). Very often eye pain is reported after surgical procedures, like PRK and LASIK. Up to 60% of patients continue to have chronic pain beyond one …
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Study to assess oral IPN60130 for the treatment of Fibrodysplasia Ossificans Progressiva (FOP) in male and female participants 5 years of age and older

5 years - 99 years
All genders
Phase 2
Interventional
The purpose of this study is to investigate the safety and efficacy of an investigational drug called IPN60130 in the treatment of FOP. IPN60130 is considered “investigational” because it has not been approved by the United States Food and Drug Administration (U.S. FDA) for the treatment of FOP.
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Study to Evaluate Safety and Efficacy of Ck3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

18 years - 99 years
All genders
Phase 3
The purpose of this study is to compare the effects of CK-3773274, and placebo, on the exercise and health status of patients with oHCM. The safety and tolerability of CK-3773274 will also be studied.
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Assessing the Efficacy and Safety of Staccato Alprazolam in Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

12 years - 99 years
All genders
Phase 3
Interventional
This research study is being conducted to learn how well Staccato Alprazolam works and how safe it is for the treatment of epilepsy. Some participants will receive a placebo.
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Evaluating the Efficacy and Safety of BMS-986263 in Adults with Compensated Cirrhosis from Nonalcoholic Steatohepatitis (NASH)

99 years or below
All genders
The purpose of this study is to test the effectiveness (how well the study drug works) and safety of BMS-986263 in participants with compensated cirrhosis from nonalcoholic steatohepatitis (NASH). The study drug BMS-986263, is investigational. An investigational drug is one that is not approved by the United States Food and …
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Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection Of Lung Malignancies.

18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this research study is to learn if the investigational study drug, pegsitacianine, helps in seeing the primary lung cancer tumor and identifying any additional cancerous tissue present in the lung for removal at the time of standard of care cancer surgery. Each participant will receive a single …
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Evaluating TRUFILL® n-Butyl Cyanoacrylate (n-BCA) Liquid Embolic System as a treatment of chronic subdural hematoma (cSDH)

18 years - 99 years
All genders
The objective of this study is to evaluate the safety and effectiveness of TRUFILLP Pn-BCA for MMA embolization in patients presenting with a cSDH compared to patients treated with standard of care management. Residual or re-accumulation of the cSDH (more than 10 mm) at 6 months as assessed by an …
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Imaging of Central Nervous System Tumors Using Indocyanine Green (TumorGlow - CNS)

18 years - 99 years
All genders
Phase 1
Interventional
The research study is being conducted to determine if a same-day intravenous (into a vein) injection of indocyanine green (ICG) detected using an imaging system, can be a useful tool in identifying and differentiating tumor tissue from normal tissues.
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Study to Evaluate LMI070/branaplam Treatment Medication in Participants with Huntington's Disease

18 years - 99 years
All genders
Interventional
This is a dose range finding safety study of Branaplam administered as weekly oral doses in participants with early manifest HD. The study aims to explore a range of doses to select a safe and tolerable dose that lowers mutant huntingtin protein (mHTT) levels in the CSF to a degree …
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