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Found 1202 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study of lurbinectedin efficacy and safety in participants with advanced or metastatic solid tumors
18 years - 99 years
All genders
Phase 2
Interventional
This research study is designed to learn more about the safety and effectiveness of lurbinectedin given to individuals who have been diagnosed with advanced (metastatic and/or unresectable) solid tumors.
 Testing novel drugs or drug combinations to treat breast cancer before surgery
18 years - 99 years
Female
A clinical trial to determine whether adding experimental agents to standard neoadjuvant paclitaxel (with or without trastuzumab), anthracycline, nad cyclosphosphamide increases the probability of pathologic complete response (pCR) over standard neoadjuvant chemotherapy for each biomarker signature established at trial entry, and to determine for each experimental agent used, the predictive …
 Strategies in Patients undergoing repeat AF ablation
18 years - 99 years
All genders
Interventional
The aim of the proposed research project is to compare the efficacy of three different ablation strategies in patients with atrial fibrillation (AF) who are undergoing their first repeat catheter ablation for recurrent AF.
 A Clinical Study to Evaluate the Efficacy and Safety of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)
18 years - 75 years
All genders
Phase 2
Interventional
The objective for this trial is to determine the effect of GB002 (seralutinib) on improving pulmonary hemodynamics in subjects with World Health Organization (WHO) Group 1 PAH who are Functional Class (FC) II and III.
 Intensive TMS for Rapid Relief of Bipolar Depression Symptoms
18 years - 99 years
All genders
The research study is being conducted to test whether using high dose spaced theta-burst rTMS (a form of transcranial magnetic stimulation) produces a significant reduction in depressive symptoms compared with sham. This project will recruit patients aged 18-70 with symptoms of bipolar depression who have failed (or not shown signs …
 JAGUAR- ObJective Analysis to GaUge EVAR Outcomes Through Randomization
21 years - 99 years
All genders
Phase 4
This post-approval study will collect safety, performance, effectiveness, and neck dilatation data on Alto Abdominal Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms and evaluate real-world outcomes in comparison to commercially available comparator devices. Penn Medicine patients with the Alto Abdominal Stent Graft System, a device …
 Improving Clinical Outcomes of Auditory Brainstem Implantation with Speech-Evoked Auditory Brainstem Responses
18 years - 99 years
All genders
The goal of this study is to improve the reliability of acquiring open-set speech recognition following ABI placement for retrocochlear deafness, to evaluate whether state of consciousness influences speech-based ABR. The researchers hypothesize that: 1) It will be possible to elicit speech-based ABR from surgically anesthetized patients. 2) Surgically anesthetized …
 DECODE Biologic-Describing the Consequences of Delays in Biologic initiation Study
18 years - 99 years
All genders
This study plans to learn more about the usage and effect of biologic medications with patients that have inflammatory bowel disease (IBD). IBD includes both Crohn’s Disease (CD) and Ulcerative Colitis (UC), which currently affects around 1.5 million Americans. Medical therapies for IBD focus on reducing the inflammation of the …
18 years - 65 years
All genders
Interventional
The research study is being conducted to test the efficacy of a new psychotherapeutic strategy, closed loop real time fMRI neurofeedback, in reducing negative attention bias and depressive symptoms. Participants are being asked to voluntarily participate in a research study because they are between the ages 18-65 and currently experiencing …
18 years - 99 years
All genders
Phase 1
The purpose of this study is to test the safety of SAR441236, a study drug that has not been tested in humans before now. The study will also look at how long SAR441236 stays in the body after one dose and after four doses. It will also look at whether …
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