The research study is being conducted to learn how violating the chest wall during Cardiothoracic surgery changes perfusion to the bone and soft tissue of the chest wall. Further, this study will investigate whether changes in perfusion are correlated with adverse clinical outcomes. If you agree to join the study, you will be asked to complete the following research procedures: 1) Undergo between three to five intra-operative injections with Indocyanine Green (ICG) during your surgery followed by non-invasive non-ionizing intra-operative imaging with fluorescence spectroscopy at the time of your surgery 2) Undergo between two to four intra-operative injections with ICG followed by non-invasive non-ionizing imaging with fluorescence imaging at the time of any subsequently required chest wall reconstruction procedures 3) Allow researchers to review your electronic medical records periodically to assess your clinical progress after surgery 4) Allow researchers to potentially use non-identifiable images of your chest wall in future publication of data collected as part of this study Your participation will last for up to 24 months dependent on duration of your standard follow up with your Cardiothoracic surgeon.

You may be eligible for this study if you meet the following criteria:

• Conditions: Cardiothoracic
• Age: 18 years - 99 years
• Gender: All