Evaluating an Investigative Drug Letermovir (Prevymis) in Adults with Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV)

Recruiting
40 years - 99 years
All
15 participants needed
1 Location

Brief description of study

The purpose of this study is to test letermovir when given to people who have both well-controlled HIV infection and asymptomatic CMV infection. This study will also gather data on the effectiveness of letermovir to reduce inflammation when compared to no anti-CMV study treatment. In addition, the study will collect information on whether you experience any side effects from the study drug. The study will last for about 1 year and 2 months (about 11 months on either letermovir or no anti-CMV study treatment and then about another 3 months of follow-up). Compensation up to $825.

Detailed description of study

The purpose of this study is to test letermovir when given to people who have both well-controlled HIV infection and asymptomatic CMV infection. This study will also gather data on the effectiveness of letermovir to reduce inflammation when compared to no anti-CMV study treatment. In addition, the study will collect information on whether you experience any side effects from the study drug. The study will last for about 1 year and 2 months (about 11 months on either letermovir or no anti-CMV study treatment and then about another 3 months of follow-up). Compensation up to $825.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Medical Research,Human Immunodeficiency Virus,HIV-1,HIV,Asymptomatic Cytomegalovirus,CMV
  • Age: 40 years - 99 years
  • Gender: All

Participants Age 40+. Diagnosed with both HIV (the virus that causes AIDS) and a positive antibody test for cytomegalovirus (CMV) (a common virus that can infect almost anyone).

Updated on 04 Aug 2024. Study ID: 851174

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