Research Study on Whether a Combination of 2 Medicines Works in People With Non-alcoholic Steatohepatitis (NASH)

Research Study on Whether a Combination of 2 Medicines Works in People With Non-alcoholic Steatohepatitis (NASH)

Research Study on Whether a Combination of 2 Medicines Works in People With Non-alcoholic Steatohepatitis (NASH)
Recruiting
18 years - 99 years
All
Phase N/A
75 participants needed
1 Location

Brief description of study

This study is being done to see if a combination of 2 medicines (called NNC0194-0499 and semaglutide) can reduce liver damage in patients with non alcoholic steatohepatitis (NASH). NNC0194-0499 is a new medicine which works in the liver. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. It also helps with weight loss and may reduce liver damage, and so prevent future liver complications. It works in a different way to NNC0194 0499. The 2 medicines may work better together than on their own. The study will also look at a combination of semaglutide and another weight-loss medicine called NNC0174-0833, which may be another treatment option for NASH.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Non-alcoholic Steatohepatitis,NASH
  • Age: 18 years - 99 years
  • Gender: All

Male or Female Age 18 or older Histological evidence of NASH

This study investigates the effects of a combination of two investigational medications on non-alcoholic steatohepatitis (NASH).

The study evaluates whether combining these medications can reduce liver damage associated with NASH.

  • Who can participate: Adults aged 18 and older with histological evidence of NASH can participate.
  • Study details: Participants will take part in a study evaluating the effects of combining two investigational medications. An inactive substance that looks like the investigational medicine but does not contain any medicine, known as a placebo, may be used for comparison.
Updated on 04 Aug 2024. Study ID: 849168

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