This study is for those diagnosed with transthyretin-mediated amyloid cardiomyopathy which is a disease caused by change in a protein called transthyretin (TTR). This change can either be sporadic which is known as wild-type (wtATTR-CM) or due to a mutation of the TTR gene which is hereditary (hATTR-CM). In both cases, these changes can cause the TTR to clump and build up in certain parts of your body such as your nervous system, stomach, intestines, and heart. This build up is called an amyloid deposit. Amyloid deposits can sometimes cause heart disease or neuropathy. When amyloid is deposited into the heart, it can result in a condition referred to as cardiomyopathy.

You may be eligible for this study if you meet the following criteria:

• Conditions: Cardiomyopathy
• Age: 18 years - 90 years
• Gender: All