Build status - In Progress

A Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy

Study on a Nerve Condition Linked to Protein Deposits

A Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Recruiting
18 years - 82 years
All
Phase 3
140 participants needed
1 Location

Brief description of study

A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy. For those with : a. Stage 1 or Stage 2 according to the Familial Amyloid Polyneuropathy (FAP) or Coutinho Stage b. Documented genetic mutation in the TTR gene c. Symptoms and signs consistent with neuropathy associated with transthyretin amyloidosis

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Transthyretin-Mediated Amyloid Polyneuropathy,neuropathy,
  • Age: 18 years - 82 years
  • Gender: All

Male or Female Age 18-82 a. Stage 1 or Stage 2 according to the Familial Amyloid Polyneuropathy (FAP) or Coutinho Stage b. Documented genetic mutation in the TTR gene c. Symptoms and signs consistent with neuropathy associated with, transthyretin.

This study investigates hereditary transthyretin-mediated amyloid polyneuropathy, focusing on evaluating the safety and efficacy of an investigational medication for treating this condition.

  • Who can participate: Adults aged 18 to 82 with Stage 1 or Stage 2 Familial Amyloid Polyneuropathy, a genetic mutation in the TTR gene, and symptoms of neuropathy can participate.
  • Study details: The study evaluates the effects of an investigational medication on the condition.
Updated on 04 Aug 2024. Study ID: 834496

Find a site

We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Preferred way of contact
Race
Ethnicity
Other language

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center