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A Pilot Phase I Randomized Study to evaluate Innate Immune Activation predictors of sustained viral control in HIV-Infected Adults Undergoing a Brief Analytical Treatment Interruption after the administration of Pegylated Interferon Alpha 2b in Combination with Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074

Recruiting
99 years or below
All
Phase 1
12 participants needed
1 Location

Brief description of study

Our pilot study will evaluate whether the activation of antiviral innate mechanisms by administration of Pegylated Interferon alpha 2b (peg-IFN-2b) when combined with two broadly neutralizing antibodies (3BNC117 and 10-1074) in HIV positive participants with well controlled viral replication can result in viral control in the absence of ART or immune based therapy during a monitored analytical treatment interruption.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Medical Research
  • Age: 99 years or below
  • Gender: All
Updated on 12 Dec 2019. Study ID: 833816

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