Found 12 Eye Disease trials
A listing of Eye Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
PD GPI MRFGUS
To demonstrate ExAblate procedure is safe and works.There is evidence in medical literature showing that by ablating a particular cluster of cells in the brain, dyskinesia (abnormal movements)&motor symptoms of PD may improve. ExAblate can be used to perform ablation more precisely in minimally invasive fashion. In this study we …
Impact of Nicotine Messaging on Beliefs and Behavior
The purpose of this study is to examine the impact of nicotine messaging on beliefs and behavior while using investigational cigarettes with either normal nicotine levels or reduced nicotine levels.
Observational Characterization of the Treatment Course of Patients With Thyroid Eye Disease
This study will: • Evaluate standard-of-care (SOC) treatment for TED in a real-world setting • Evaluate effectiveness of the treatment in terms of protrusion of the eyeball (proptosis) • Show if the SOC treatment has any effect on eye anatomy and function and fi the appearance of the subject’s eyes …
A Multiple-Site Phase 1/2 Safety and Efficacy Trial of a Recombinant Adeno-associated Virus Vector Expressing CNGB3 (rAAV2tYF-PR1.7-hCNGB3) in Patients with Congenital Achromatopsia Caused by Mutations in the CNGB3 Gene
Achromatopsia is an inherited retinal disorder characterized by markedly reduced visual acuity, nystagmus, photoaversion (intolerance to bright light), a small central scotoma, eccentric viewing, and complete or severe loss of color discrimination. The genetic mutations of the disease can be established in the majority of individuals. Approximately 50% are caused …
Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients
Primary Objectives: 1. To establish the prevalence of neuropathic corneal pain in patients with ocular surface discomfort. 2. To assess the overlap of neuropathic corneal pain with dry eye disease in patients in diseases that are currently thought to be mutually exclusive. 3. To establish the prevalence of subtypes of …
Zoster Eye Disease Study (ZEDS): A multi-center randomized double-masked placebo-controlled study of valacyclovir in immunocompetent subjects with a history of dendriform epithelial keratitis stromal keratitis endothelial keratitis and/or iritis due to Herpes Zoster Ophthalmicus (HZO) within the year prior to enrollment.
Request to rely on the lead site IRB, see attached documents
Study to evaluate SAF312 eye drops in the treatment of post-operative corneal induced chronic pain (CICP) following Photorefractive Keratectomy (PRK) or Laser-assisted in Situ Keratomileusis (LASIK) surgeries
Many patients suffer from acute ocular pain due to different problems, however there is no available treatment for chronic eye pain (long lasting eye pain). Very often eye pain is reported after surgical procedures, like PRK and LASIK. Up to 60% of patients continue to have chronic pain beyond one …
Adalimumab vs. Conventional Immunosuppression for Corticosteroid-sparing for Uveitis (ADVISE) Trial
The ADalimumab Vs. conventional ImmunoSupprEssion for uveitis (ADVISE) Trial is a randomized, comparative effectiveness trial comparing adalimumab to conventional agent immunosuppression for patients with non-infectious, intermediate, posterior, and panuveitides. Scheie Eye Institute, the Department of Ophthalmology, University of Pennsylvania will not enroll any patients under 18 years of age.
COAST (COAST)
The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting …
Assessment of T4032 (unpreserved bimatoprost 0.01%) versus Lumigan 0.01% in ocular hypertensive or glaucomatous patients
The purpose of this study is to find out about the safety and efficacy of T4032, which is a preservative-free formulation of bimatoprost (0.01%) for the treatment of glaucoma or ocular (eye) hypertension. There will be 5 to 6 study visits and participation will last up to 12 weeks (120 …
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