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Found 97 Vision Loss trials

A listing of Vision Loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
Phase 3
The study will enroll subjects who have completed Study M16-067 or Study M16-065 and have achieved clinical response, defined as decrease from Baseline of induction study of Adapted Mayo score greater than or equal to 2 points and greater than or equal to 30%, PLUS a decrease in rectal bleeding …
 A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
40 years - 90 years
All genders
Interventional
The purpose of this study is to evaluate the safety and efficacy of CNTX-6970. The target population is adults between 40 - 90 years old who have moderate to severe knee pain related to OA. The study drug is being compared to Celebrex, an FDA approved drug used to treat …
 A Prospective Randomized  Double-Blind  Placebo-Controlled Crossover Study to Evaluate the Clinical Utility of the Vascular Health Profile Diagnostics Assay (VHP) in Assessment of Response to Administration of a HMG-CoA reductase inhibitor (statin) as Primary Prevention in Patients with Asymptomatic Atherosclerosis
1 years - 99 years
All genders
This is a prospective, single-center, randomized double-blind, placebo-controlled, crossover study conducted in the United States (US). Patients will be randomized into two treatment sequences (treatment A in period 1, followed by treatment B in period 2, or treatment B in period 1, followed by treatment A in period 2). At …
 A Phase 2  Multi-center  Randomized  Double-Blind  Placebo-Controlled  Dose Range Finding Study to Evaluate the Safety  Hemodynamic Effects and Efficacy of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects who have Diabetic Foot Ulcer with Peripheral Arterial Disease
1 years - 99 years
All genders
Phase 2
This is a Phase 2, randomized, double-blind, placebo-controlled, dose range finding study in subjects who have DFU with PAD. The study will enroll approximately 24 subjects. Two dose levels of PDA-002 (3 x 106 and 30 x 106 cells) versus placebo will be evaluated in 1:1:1 randomization approach. Subjects will …
99 years or below
All genders
A study to investigate efficacy and safety of OG-6219 BID in 3 dose levels compared with Placebo in participants aged 18 to 49 with moderate to severe endometriosis-related pain
 BEAT-MS Multiple Sclerosis Trial
18 years - 55 years
All genders
This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio.All participants will be followed …
18 years - 60 years
All genders
Interventional
This study evaluates the effect of a cognitive remediation program on neurocognitive, social cognitive and metacognitive functions designed for patients living with a schizophrenia spectrum disorder.
 Adherence to HIV Therapy in Heroin Addicts Oral vs. Extended Release Naltrexone-Test
18 years - 64 years
All genders
Phase 2
Interventional
Substance use, particularly the compulsive behaviors associated with addiction, lead to unhealthy behaviors including non-adherence to antiretroviral therapy (ART) and treatment failure. High on the list of disorders leading to non-adherence is heroin addiction as a wide range of impulsive, high-risk behaviors accompanies it. The science of adherence would be …
 Study to Evaluate Nipocalimab in Participants with Active Idiopathic Inflammatory Myopathies
18 years - 90 years
All genders
Phase 2
Interventional
The purpose of this study is to see if the investigational drug nipocalimab is safe and useful for treating patients with active Idiopathic Inflammatory Myopathies (IIM).  Another purpose is to find out if nipocalimab can cause side effects, which are unexpected or unwanted reactions from taking a drug.   An …