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Found 92 Vision Loss trials

A listing of Vision Loss medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 80 years
All genders
Phase 2
SAR443820 is a selective, orally bioavailable, central nervous system (CNS)-penetrant, receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitor. The aim of this Phase 2 study is to determine the efficacy, safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of SAR443820 in treating adult participants with amyotrophic lateral sclerosis (ALS).
99 years or below
All genders
The objective of this clinical trial is to assess whether ladarixin treatment is effective in preserving -cell function and delaying the progression of T1D in adolescent and adult patients. The safety of ladarixin in the specific clinical setting will be also evaluated.
 A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS-IgAN)
18 years - 80 years
All genders
Phase 3
This study will use a new investigational study drug called OMS721 in people with Immunoglobulin A (IgA) Nephropathy. This kidney disease produces abnormal amounts of a protein called IgA in the kidney that damage the filtering units or glomeruli. Glomeruli are tiny filtering units in the kidney that remove excess …
 A Randomized, Double-Blind, Placebo Controlled Study to Evaluate Efficacy and Safety of Nefecon in Patients with Primary IgA Nephropathy at Risk of Progressing to End-Stage Renal Disease (NefIgArd)
1 years - 100 years
All genders
Phase 3
The research study is being conducted to see how well the investigational drug, Nefecon, works for the treatment of your kidney disease and more specific for patients with "primary immunoglobulin A nephropathy," called IgAN.
 PROTECT- study of the efficacy and safety of sparsentan for the treatment of Immunoglobulin A (IgAN) nephropathy
18 years - 99 years
All genders
Phase 3
Immunoglobulin A nephropathy (IgAN) is a rare disease that affects the kidneys, mostly in teens and adults. Kidneys are important to your health because they filter waste materials such as salts, toxins and water out of the blood. The waste is passed out of your body as urine (pee). IgAN …
16 years - 100 years
Male
Phase 3
The primary objective of the PURPOSE2 study is to evaluate the efficacy of lenacapavir (LEN) in preventing the risk of contracting human immunodeficiency virus (HIV). The study will be conducted in 2 parts: a cross-sectional study (Incidence Phase) and a double-blind, randomized study (Randomized Phase).1) The Incidence Phase will include …
18 years - 74 years
All genders
Phase 3
Placebo-Controlled, Study to Evaluate the Efficacy and Safety of Seltorexant 20 mg as Adjunctive Therapy to Antidepressants in Adult and Elderly Patients with Major Depressive Disorder with Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy and an Open-labeled Long-term Safety Extension Treatment with Seltorexant
18 years - 50 years
All genders
Phase 2
The main purpose of this study is to learn if a vaccine that is given as two shots (injections) to prevent spinal meningitis (an infection of the lining of the brain and spinal cord caused by Neisseria meningitidis type B) might also work in preventing gonorrhea (caused by Neisseria gonorrhoeae). …
45 years - 89 years
All genders
Interventional
This is a pragmatic, double-blind, randomized, controlled trial, to evaluate the effect of implementing a CADs system within the routine clinical practice of Canadian healthcare institutions.The main hypothesis of this study is that the ADR in the operating room equipped with the GI genius CADe system will be significantly higher …
 A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants With Early Parkinson's Disease (PADOVA)
50 years - 85 years
All genders
Phase 2
Interventional
This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab versus placebo in participants with Early Parkinson's Disease (PD) who are on stable symptomatic PD medication.
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