Found 10 Opioid Use Disorder trials
A listing of Opioid Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
![Effects of opioid use disorder and non-fatal overdose on tau pathology; a [18F]PI-2620 PET/CT study](/media/img/trial_thumbnails/img/siteimg/Pavillion_PennMed_Marketing_a.jpg)
Effects of opioid use disorder and non-fatal overdose on tau pathology; a [18F]PI-2620 PET/CT study
This study is being conducted to learn more about how opioid use and opioid overdose affects tau levels in the brain. Tau is a protein in the brain that helps stabilize nerve cells structure. We will study tau levels in the brain using a type of Positron Emission Tomography (PET/CT) …
Pilot Study of a Multi-System Analysis of Opioid Receptor Binding
The purpose of this research is to learn more about mu opioid receptor (MOR) binding in the brain and body. This study will enroll up to 60 adults in three cohorts of up to 20 participants each: Cohort 1: Subjects with a lifetime diagnosis of Opioid Use Disorder (OUD) on …
General Screening Protocol for Affected and Unaffected Participants in Studies of Substance Use Disorders
The goal of this study is to evaluate individuals with and without substance use disorder (SUD) to determine whether it is safe and appropriate for them to participate in a clinical trial, imaging study, or other research protocol that matches the participants’ interests and eligibility. Our goal is to enroll …
Open label comparison of injectable buprenorphine (CAM2038 Brixadi ) and naltrexone (Vivitrol ) for opioid use disorder
Compare brain fMRI response to injectable extended-release buprenorphine (Brixadi, XR-BUP) and naltrexone (XR-NTX, Vivitrol) Our primary outcome combines adherence to treatment and the frequency of illicit opioid use during treatment. The primary outcome is a binary indicator of treatment success: Participants who provide 2 weekly UDS positive for opioids or …
Evaluation of in vivo Neuroinflammation Using 18F-NOS (PET/CT) in HIV Positive and Negative Subjects with Opioid Use Disorder and Healthy Controls
Study Purpose: The goal of this study is to learn more about how opiate use and HIV affects inflammation in the brain. We will study this using a type of Positron Emission Tomography (PET/CT) scan using a radioactive imaging drug called 18F-NOS that can be used to measure inflammation in …
A Pilot Proof of Concept Single-Center Study of the Use of Oritavancin in Systemic Staphylococcus aureus Infections in Patients with Opioid Use Disorder
The study participants will be in the study for approximately 2 months including the screening, intervention phase and the 6 weeks of follow-up time
Effects of Mu-opiate receptor engagement on the persistence of HIV-associated activation and viral reservoirs in individuals receiving medication assisted treatment for opioid use disorder
Both HIV infection and exposure to opioids, including intravenous heroin in people who inject drugs (PWIDs), are associated with systemic immune activation due to, at least partially, dysbiosis and increased microbial translocation from the gut. Medication-assisted treatment (MAT) approaches based on the administration of Opioid Receptor (MOR) agonists (e.g. methadone) …
RIDE+
This research study will help us see whether providing medical services in a mobile unit will help persons who inject drugs (PWID) start and stay on anti-HIV medicines and medicines for opioid use disorder better.
Emergency Department-Initiated Buprenorphine Validation Network Trial
The purpose of this research study is to compare two versions of the same medication buprenorphine, (commonly known as Suboxone) used to treat opioid use disorder, in patients in the Emergency Department (ED). One form of the medication is a slow-release form of buprenorphine (CAM2038) that lasts for about 7 …
The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions: Randomized Trial
We are interested in comparing 3 care conditions to determine which condition is best to help people with opioid use disorder (OUD) and mental illness reduce their drug use and improve their psychiatric symptoms. The model we are testing is called collaborative care. This model uses a team-based approach in …
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