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Found 63 Neoplasm Metastasis trials

A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Safety and Efficacy of IONIS-FB-Lrx in Patients  With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
55 years - 99 years
All genders
Phase 3
Interventional
The purpose of this study is to assess the Safety and Efficacy of IONIS-FB-Lrx patients with Geographic Atrophy secondary to Age Related Macular Degeneration
 An Extension Study to Assess the Long-Term Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB067 Administered to Previously Treated Adults with Amyotrophic Lateral Sclerosis Caused by Superoxide Dismutase 1 Mutation
18 years or above
All genders
Phase 3
Interventional
The primary objective of the study is to evaluate the long-term safety and tolerability of BIIB067 (tofersen) in participants with amyotrophic lateral sclerosis (ALS) and confirmed superoxide dismutase 1 (SOD1) mutation. The secondary objectives are to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), biomarker effects, and efficacy of BIIB067 administered to …
18 years - 99 years
All genders
Phase 2
Interventional
This study involves metastatic, stage 4 cancer, that has spread to your abdominal cavity and your cancer surgeon recommends surgery to remove cancer tumors from your abdomen. The purpose of this research study is to learn if the investigational study drug, pegsitacianine, helps in seeing the metastatic cancer disease left …
 A071701 Genomically-Guided Treatment Trial in Brain Metastases
18 years - 99 years
All genders
Interventional
This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK or PI3K. Medications that target these genes such …
 Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases
18 years - 99 years
All genders
Phase 2
Interventional
The overall objectives of the study is to establish visual image interpretation criteria for 18F-fluciclovine PET in detecting recurrent brain metastases and to establish other image interpretation criteria for 18F-fluciclovine PET in detecting recurrent brain metastases.
70 years - 99 years
All genders
Phase 2
Interventional
This study will test danicopan, a new drug that is being developed by Alexion to slow down progression of GA. The goals of this study are as follows: • To find out whether danicopan can slow the rate of GA disease progression, and in turn slow the loss of visual …
 CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer
99 years or below
All genders
Phase 3
SGM-101 is a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody. What this means is that part of SGM-101 is a chemical that is attracted to and will attach to the cells of your cancer. Another part of SGM-101 is a chemical that will glow when infrared light is shined on it. …
18 years - 99 years
All genders
Phase 3
The research study is being conducted to show how effective an imaging drug called 18F-fluciclovine can be used to image uptake before planned surgery. Fluciclovine is a drug used with an imaging test called Positron Emission Tomography/Computed Tomography (PET/CT). PET scan is for detecting suspected recurrence of brain metastases in …
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