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Found 22 Inflammation trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 69 years
All genders
Phase 2
Are you still experiencing celiac disease symptoms despite your best efforts to follow a gluten-free diet?The goal of this phase 2 clinical trial is to test the safety and effects of the investigational medication PRV-015. In combination with a gluten-free diet, PRV-015 aims to reduce symptoms and intestinal inflammation caused …
 Investigational COVID-19 Vaccine Trial
18 years - 60 years
All genders
Phase 1
This clinical research trial is being conducted to find out whether the administration of two investigational dMab products (not approved by the US FDA) with an investigational device is safe, tolerated, and can produce enough antibodies in your blood that may indicate the ability to prevent infection of COVID-19.
18 years - 75 years
All genders
The purpose of this study is to see if the study drug ABBV-154 is safe and able to treat subjects with moderately to severely active Crohn's Disease who have an inadequate response to or were intolerant of prior biologics. ABBV-154 is an antibody-drug conjugate, which means it is composed of …
99 years or below
All genders
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes, which may be useful in the diagnosis, prognosis, and treatment of giant cell arteritis (GCA; temporal arteritis). Study participants are eligible if …
99 years or below
All genders
Both HIV infection and exposure to opioids, including intravenous heroin in people who inject drugs (PWIDs), are associated with systemic immune activation due to, at least partially, dysbiosis and increased microbial translocation from the gut. Medication-assisted treatment (MAT) approaches based on the administration of Opioid Receptor (MOR) agonists (e.g. methadone) …
18 years - 99 years
All genders
Phase 1
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
 Study Evaluating the Safety and Efficacy of Itacitinib in Participants With Bronchiolitis Obliterans Syndrome Following Lung Transplantation
99 years or below
All genders
Phase 1
Normal 0 false false false EN-US X-NONE X-NONE You are being invited to participate in a research study because you have Bronchiolitis Obliterans Syndrome. Bronchiolitis Obliterans Syndrome (BOS) is a long term (chronic) rejection process that can occur in the transplanted lungs.  Itacitinib works by blocking your body from producing …
 Trauma Induced Coagulapathy and Inflammation
99 years or below
All genders
While a number of factors are known to be associated with the development of trauma induced coagulopathy (TIC), inflammation, and multi-organ failure, we currently cannot predict which patients are at risk for developing these life-threatening conditions with any certainty. In this prospective observational study, we will investigate the many factors …
 Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging  HIV Infection and Inflammation
40 years - 99 years
All genders
Interventional
This study will look at the relationships between HIV infection, age and the immune system, and how these relate to the development of non-infectious illnesses such as heart disease, kidney disease, cancer, memory problems, and diabetes. Further, we will look at how demographic factors, behaviors, and social factors like social …
18 years - 99 years
All genders
Interventional
Parkinson’s disease is a chronic disease of the nervous system that gets worse over time. Available treatments cannot stop or slow down the worsening over time. Some evidence suggests that people with Parkinson’s disease may have more inflammation in the brain. This is thought to be one of the reasons …
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