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Found 5 Huntington's Disease trials

A listing of Huntington's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

99 years or below
All genders
PROOF-HD is a placebo-controlled (double blind) multicenter Phase 3 trial of Pridopidine in Huntington Disease patients. Recruitment: 480 participants at 60 sites, a target of 8 participants per site. Procedures include administration of study drug or placebo in tablet form twice daily for a period of 67-80 weeks with option …
25 years - 65 years
All genders
Interventional
This is a study that evaluates SAGE-718 in participants with Huntington's Disease.
18 years - 99 years
All genders
Interventional
This is a dose range finding safety study of Branaplam administered as weekly oral doses in participants with early manifest HD. The study aims to explore a range of doses to select a safe and tolerable dose that lowers mutant huntingtin protein (mHTT) levels in the CSF to a degree …
 CILT + HD-tDCS as a Potential Treatment for Primary Progressive Aphasia
45 years - 80 years
All genders
Phase 2
Primary Progressive Aphasia, or PPA, is a neurodegenerative disease that affects language abilities. A person with PPA may have difficulties speaking, understanding speech, reading, or writing, and these difficulties worsen over time.The purpose of this study is to determine whether a form of non-invasive brain stimulation called High-definition Transcranial Direct …
 ConsCIOUS2: A Prospective Study of the Isolated Forearm Technique Commands  Long-term Sequelae and Electroencephalograph Correlates Following Laryngoscopy and Intubation in patients 18 - 40 years of age
99 years or below
All genders
This a multi-center prospective cohort study of a series of commands surveying responsiveness following laryngoscopy and intubation. Clinical care will not be controlled and will be left to local policy. We will also collect routinely recorded clinical data to frame the observations about IFT responsiveness (please see list below and …