Found 559 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a Phase 2 open-label, single-arm design with dose escalation by subject cohort and with the potential for individual titration (dose increase or decrease) within each cohort. Five PTG-300 dose levels/regimens are planned to be tested for each subpopulation of beta-thalassemia (NTD and TD) on separate arms: Cohort 1: …
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes, which may be useful in the diagnosis, prognosis, and treatment of giant cell arteritis (GCA; temporal arteritis). Study participants are eligible if …
This is a Phase 3b, multicenter, open-label extension (OLE) study to evaluate the efficacy and safety of Nefecon treatment in patients with IgAN who have completed the Phase 3 Study Nef 301 and continue to be treated with a stable dose of RAS inhibitor therapy (ACEIs and/or ARBs). Patients who …
Blood is an easily accessible source of tumor cell free (cf) DNA. Both normal and malignant cells shed DNA into the circulation, and advanced genomics technologies can analyze tumor cfDNA, making blood a source of real-time genomic tumor profiling. For ccRCC patients, peripheral blood will be obtained as part of …
To document the long-term safety and tolerability profile of osilodrostat in routine clinical practice over a 3 year follow up period in patients with endogenous Cushing's Syndrome. The study population is male and females 18 years or greater who are being treated with osilodrostat.The primary data source will be the …
PURPOSE/DESCRIPTION: The main objective of this study is to clinically and radiographically compare the periodontal phenotype (hard and soft tissue) post orthodontic movement on surgical sites using a corticotomy-facilitated bone augmentation approach. We will compare sites grafted with collagen matrix and allograft bone graft material (test group) to the surgical …
This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio.All participants will be followed …
The primary objective of this study is to investigate the superiority of chronic LBBAP compared to traditional right ventricular (RV) septal pacing in patients with high-degree conduction disease after transcatheter aortic valve replacement (TAVR). All patients enrolled in this study, have undergone TAVR within 2 weeks, developed high-grade conduction disease, …
The research study is being conducted to test the study drug PB2452 to see if it is safe and will reverse the bleeding effects of Brilinta® (also known as ticagrelor). Candidates must be taking Brilinta® (ticagrelor) or show intake within the past 3 days. They will be considered for participation …
This is a phase II, open-label study of ONC201 in adults with recurrent high- grade glioma. Subjects for this study will be recruited from the patient population that present to the Penn Brain tumor center- Department of Neurosurgery or Department of Medicine division of Hematology/ Oncology for evaluation and treatment …
