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Found 19 Cancer Treatment trials

A listing of Cancer Treatment medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Cancer Therapy Risk-Reduction with Intensive Systolic BP Management (CARISMA)
18 years - 99 years
All genders
Phase 2
Interventional
This phase II trial studies how well intensive blood pressure management works in decreasing systolic blood pressure in patients with kidney or thyroid cancer that has spread to other places in the body (metastatic) who are starting anti-angiogenic tyrosine kinase inhibitor cancer therapy. This study is being done to find …
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Online study
18 years or above
Male
Phase 3
Interventional
This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective compared to standard of care alone in …
99 years or below
All genders
Phase 1
This is a Phase 1 study that will evaluate the effectiveness of TPST-1120. Subjects may receive TPST-1120 alone or in combination with nivolumab. Subjects eligible to participate are those with advanced solid tumors.
 SPLASH: Study Evaluating Metastatic Castrate Resistant Prostate Cancer Treatment Using 177Lu-PNT2002 PSMA Therapy After Second-line Hormonal Treatment
18 years - 99 years
Male
Phase 3
Interventional
This is a research study for those with metastatic castration-resistant prostate cancer (mCRPC) that has progressed following treatment with prior therapy and cannot receive or refuse to receive chemotherapy. The purpose of this research study is to learn about the safety and effectiveness of 177Lu PNT2002, an investigational agent being …
 Understanding COVID-19 vaccine responses in the setting of immunotherapy (Sub-study)
18 years - 99 years
All genders
This research is a sub-study to the “Understanding influenza vaccine responses in the setting of immunotherapy” protocol (parent study). This sub-study is open to only those participants that have consented to be part of the above parent study. This study is designed to better understand antibody responses in the setting …
 Genetics and Heart Health after Cancer Therapy
99 years or below
All genders
The overall objective of this study is to use patient-centered in vitro and in vivo models to answer the fundamental question of whether or not pathogenic mutations in BRCA1/2 result in an increased risk of CV disease. We plan to enroll 100 BRCA1/2 mutation carriers who have been treated for …
 Phase Ia/Ib Dose-Escalation and Dose-Expansion Study Evaluating the Safety  Pharmacokinetics  and Activity of GDC-6036 as a Single Agent and in Combination With Other Anti-cancer Therapies in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
18 years - 99 years
All genders
Phase 1
Interventional
This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.
18 years - 99 years
All genders
The primary purposes of this research study are to determine the safety and tolerability of dose levels of the investigational drug, XmAb20717, and if XmAb20717 works in treating advanced solid tumors that have progressed after treatment with standard cancer therapies or solid tumors for which there are no appropriate therapies …
 UPCC 06717 / AMC 101: A Pilot Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas
18 years - 64 years
All genders
Phase 1
Non-Hodgkin lymphoma  is a potentially curable condition with standard cancer treatment drugs (chemotherapy) and steroids. Standard lymphoma treatment includes chemotherapy, or cancer-fighting drugs, called etoposide, vincristine, cyclophosphamide, prednisone and doxorubicin (called EPOCH).  
 A Randomized   Study of Amcenestrant (SAR439859) Plus Palbociclib Versus Letrozole Plus Palbociclib for the Treatment of Patients With ER (+)  HER2 (-) Breast Cancer
18 years - 99 years
All genders
Phase 3
Interventional
The purpose of the study is to evaluate whether SAR439859 (an experimental hormonal treatment), in combination with palbociclib is a better option compared to letrozole (a standard hormonal treatment), in combination with palbociclib, in terms of efficacy and tolerance for treating patients with ER (+), HER2 (-) breast cancer. Eligible …
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