Found 11 Kidney Transplantation trials
A listing of Kidney Transplantation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Studying imlifidase in comparison to the standard of care in the management of highly sensitized kidney transplant patients.
The purpose of this study is to demonstrate the efficacy and safety of imlifidase in comparison to the standard of care (SoC) in the management of highly sensitized transplant patients.
TruGraf Long-term Clinical Outcomes Study
The purpose of this study is to evaluate post-transplant clinical outcomes in recipients of kidney transplants who are undergoing TruGraf® and TRAC monitoring. These tests are commercially available blood tests that may help better monitor rejection. Targeted population are kidney transplant recipients. Procedures include blood will be drawn for TruGraf® …
NONINTERVENTIONAL EXTENSION STUDY FOR PATIENTS TREATED IN STUDY R5459-RT-1944 WITH REGN5459 OR REGN5458 (BCMA CD3 BISPECIFIC ANTIBODIES) WHO RECEIVE A KIDNEY TRANSPLANT
The primary objective of the study is to assess adverse events (AEs) and serious adverse events (SAEs) in kidney transplant recipients previously treated with REGN5459 or REGN5458 in the R5459-RT-1944 study. The primary endpoint for this study is the incidence of AEs and SAEs over a 12-month period, starting at …
CAR-T Cell Therapy for Desensitization in Kidney Transplantation
This research study is for people who have been waiting for a kidney transplant for at least one year, and who have a cPRA of 99.5% or higher. Having a cPRA of 99.5% or higher means that your immune system would reject 99.5% of kidneys available for transplant. The study …
PTAAK- study of pulse wave velocity evaluation tacrolimus time in therapeutic range and co-efficient of tacrolimus variation of African American kidney transplant recipients receiving immediate release tacrolimus capsules (IR-Tac) or extended release tacrolimus tablets (LCPT)
The primary purpose of this study is to evaluate the pulse wave velocity and vascular compliance measurements at the beginning and the end of the study in African American kidney transplant recipients taking either Envarsus XR® (extended release tacrolimus) tablets administered once-daily after transplantation or immediate release generic tacrolimus capsules …
HOPE in Action Prospective Multicenter Clinical Trial of HIV+ Deceased Donor Kidney Transplants for HIV+ Recipients
Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …
Kidney Transplantation in Recipients and Donors with HIV: Long Term Follow up Study
The purpose of this study is to study how well patients that receive a kidney from an HIV+ organ donor do over 10 years compared to patients that receive a kidney from an HIV- donor. People 18 years of age and older with end-stage renal disease and HIV, and who …
Sample Collection for Prospera Enhancement
The research study is being conducted to learn how well a test called Prospera can detect rejection in a transplanted kidney after a biopsy. If results of the biopsy do not indicate rejection, the study team will follow your condition by reviewing your clinical visits for one year, at which …
A trial of transplanting Hepatitis C-viremic kidneys into Hepatitis C-Negative kidney recipients
The THINKER-NEXT research study is being done to determine whether it is safe to give a kidney transplant from a donor with hepatitis C to a patient without hepatitis C. The recipient will then be given a drug called Epclusa for 12 weeks to treat hepatitis C. Patients who are …
A DOSE ESCALATION AND PROOF-OF-CONCEPT STUDY OF REGN5459 OR REGN5458 (BCMA CD3 BISPECIFIC ANTIBODIES) FOR DESENSITIZATION OF CHRONIC KIDNEY DISEASE PATIENTS IN NEED OF KIDNEY TRANSPLANTATION WHO ARE HIGHLY SENSITIZED TO HUMAN LEUKOCYTE ANTIGEN
Please see Section 2 of the full study protocol. Please see Section 4.1 of the full study protocol Please see Section 4.2 of the full study protocol.
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