Found 13 Esophageal Disorders trials
A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Personalized Atrial Fibrillation Ablation with Ablation Index Adapted to Left Atrial Wall Thickness: The Ablate-by-LAW Pilot Study
This study will use ADAS 3D LA™ software modules on your cardiac computed tomography angiography (CTA) to analyze Left Atrial Wall Thickness (LAWT) and the distance from the LA to the Esophagus (LA DIST). A CTA is a noninvasive test used to focus on coronary arteries. It allows doctors to …
Pilot Study of EsoCheck Compared to Biopsies and Brush Cytology During Endoscopy for Evaluation of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus that can lead to remodeling and stricture formation. To assess response to therapy, upper endoscopy (EGD) with biopsies is performed. This can lead to multiple EGDs, which are invasive and costly. There is currently a substantial unmet need for …
A Multicenter Randomized Controlled Trial of Surveillance vs. Endoscopic Therapy for Barretts Esophagus with Low-grade Dysplasia
To compare the effectiveness of two approaches for the management of BE and LGD, endoscopic surveillance and endoscopic eradication therapy (EET), using accepted clinical endpoints of neoplastic progression [high-grade dysplasia (HGD)/mucosal esophageal adenocarcinoma (EAC)/invasive EAC] as determined by a blinded central adjudication committee
A Pilot Study of Diffusion Weighted MRI to Assess Esophageal Tumor Response to Neoadjuvant Chemoradiation
The purpose of this study is to determine if a particular Magnetic Resonance Imaging (MRI) called Diffusion Weighted (dwMRI)) will detect changes in your tumor before and during treatment with chemotherapy and radiation for esophageal cancer. We used the dwMRI because it has been used in other types of cancers …
The HepQuant SHUNT Liver Diagnostic Kit for Likelihood of Large Esophageal Varices: The SHUNT-V Study
The purpose of the HepQuant SHUNT study is to validate the Disease Severity Index (DSI) from the HepQuant SHUNT Test for likelihood of large esophageal varices by comparing the SHUNT test to the current standard of care, EGD, in patients with chronic liver disease.
Utility of Esophageal Cooling Therapy for the Prevention of Thermal Injury During Atrial Fibrillation Ablation: an investigator initiated randomized blinded single center pilot study
This is a small scale pilot study to evaluate if esophageal cooling using the Attune Medical Esophageal Heat Transfer Device (EnsoETM) limits the frequency or severity of thermal injury during catheter ablation of atrial fibrillation. This prospective, randomized study will include 40 patients with symptomatic AF undergoing index PVI at …
An induction and maintenance study to evaluate the efficacy and safety of cc-93538 in adult and adolescent subjects with eosinophilic esophagitis.
Eosinophilic Esophagitis is a chronic, allergic, inflammatory disorder of the esophagus . The allergic substance, which is called an, ‘allergen’, is often not known, and there may be more than one allergen causing your condition. For people with Eosinophilic Esophagitis, the allergen is usually something in the diet, or something …
Assessing radioactive imaging agent NDX-3315 in healthy adult participants and patients with eosinophilic esophagitis
This is a research study to evaluate whether NDX-3315, an investigational diagnostic agent, can be used to detect inflammation (swelling, redness, irritation) in the esophagus. We are inviting participants with confirmed EoE and healthy volunteers to this study. Qualified participants between the ages of 18 and 65 will receive the …
A Randomized Double-Blind Parallel Placebo-Controlled Study of the Efficacy Safety and Tolerability of Dupilumab in Adult Patients with Active Eosinophilic Esophagitis
This is a multicenter, randomized, double-blind, placebo-controlled, 2-arm, parallel-group, proof-of-concept study. The primary purpose of this study is to evaluate the effect of dupilumab on relieving EoE clinical symptoms and reducing esophageal inflammation in adults. Currently there is no regulatory-approved endpoint for drug registration for this indication. Published clinical trials …
Evaluation of Outcomes from Treatment of Benign or Malignant Gastroesophageal Diseases
This study will be a retrospective chart review of patients who have been diagnosed with benign or malignant pancreatic disease under the practice of Dr. Rohan Jeyarajah, M.D., Dr. Houssam Osman M.D., and Dr. Edward Cho M.D., Sc.M. at Methodist Health System Hospital in Richardson, Texas. The Investigators plan to …
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