Found 13 Esophageal Disorders trials
A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study will use ADAS 3D LA™ software modules on your cardiac computed tomography angiography (CTA) to analyze Left Atrial Wall Thickness (LAWT) and the distance from the LA to the Esophagus (LA DIST). A CTA is a noninvasive test used to focus on coronary arteries. It allows doctors to …
The purpose of this study is to compare the effects of atezolizumab plus tiragolumab versus atezolizumab plus placebo or double placebo on subjects with esophageal cancer who have had at least 2 cycles of chemoradiotherapy without progression of their disease. Subjects with unresectable, locally advanced esophageal cancer will receive either …
Eosinophilic esophagitis (EoE) is a chronic inflammatory condition of the esophagus that can lead to remodeling and stricture formation. To assess response to therapy, upper endoscopy (EGD) with biopsies is performed. This can lead to multiple EGDs, which are invasive and costly. There is currently a substantial unmet need for …
To compare the effectiveness of two approaches for the management of BE and LGD, endoscopic surveillance and endoscopic eradication therapy (EET), using accepted clinical endpoints of neoplastic progression [high-grade dysplasia (HGD)/mucosal esophageal adenocarcinoma (EAC)/invasive EAC] as determined by a blinded central adjudication committee
The purpose of the HepQuant SHUNT study is to validate the Disease Severity Index (DSI) from the HepQuant SHUNT Test for likelihood of large esophageal varices by comparing the SHUNT test to the current standard of care, EGD, in patients with chronic liver disease.
The purpose of this study is to test the effects of the research study drug Telomelysin (OBP-301) in combination with pembrolizumab in advanced or metastatic gastric or gastroesophageal junction (GEJ) cancer. Eligible subjects are those with advanced or metastatic cancer of the stomach or junction between the stomach and esophagus.
The purpose of this study is to determine if a particular Magnetic Resonance Imaging (MRI) called Diffusion Weighted (dwMRI)) will detect changes in your tumor before and during treatment with chemotherapy and radiation for esophageal cancer. We used the dwMRI because it has been used in other types of cancers …
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. This trial is open to Penn Medicine's Abramson Cancer Center patients only. Please contact the …
This is a small scale pilot study to evaluate if esophageal cooling using the Attune Medical Esophageal Heat Transfer Device (EnsoETM) limits the frequency or severity of thermal injury during catheter ablation of atrial fibrillation. This prospective, randomized study will include 40 patients with symptomatic AF undergoing index PVI at …
Eosinophilic Esophagitis is a chronic, allergic, inflammatory disorder of the esophagus . The allergic substance, which is called an, ‘allergen’, is often not known, and there may be more than one allergen causing your condition. For people with Eosinophilic Esophagitis, the allergen is usually something in the diet, or something …
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