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Found 33 Diabetes Mellitus, Type 2 trials

A listing of Diabetes Mellitus, Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults.
18 years - 39 years
All genders
Phase 1
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
 CureGN-Diabetes: Ancillary Study to CureGN
18 years - 99 years
All genders
Interventional
There are several different types of glomerular diseases, such as minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), and immunoglobulin A nephropathy (IgAN). Over time, these diseases may cause kidney damage. Because these kidney diseases are rare, it is difficult for individual researchers to gather a large …
18 years - 65 years
All genders
Phase 3
Interventional
The Study Product we are testing in this research study is called STx-02. This study is being done to learn more about how safe, tolerable and effective the Study Product is in participants with T1D with impaired awareness of low blood sugar and who have severe hypoglycemia. Participation could last …
18 years - 65 years
All genders
Phase 1/2
Interventional
This study will evaluate the safety, efficacy and durability of SR-02 administered to the omentum of patients of Type 1 diabetes with severe recurrent hypoglycemia. The study will also help establish the optimal treatment dose. Although this study is open to patients with all HLA or blood types, immunosuppression to …
 Noninvasive Quantification of Renal Oxygen Utilization in Early Kidney Disease
40 years - 59 years
Accepts healthy volunteer
All genders
PURPOSE/DESCRIPTION: The purpose of this study is to measure how much oxygen is used by the kidneys. The kidneys play an important role in removing waste products from the body. In people with chronic kidney disease and diabetes, the kidneys do not function normally and have changes in oxygen consumption. …
 Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging  HIV Infection and Inflammation
40 years - 99 years
All genders
Interventional
This study will look at the relationships between HIV infection, age and the immune system, and how these relate to the development of non-infectious illnesses such as heart disease, kidney disease, cancer, memory problems, and diabetes. Further, we will look at how demographic factors, behaviors, and social factors like social …
 Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
18 years - 99 years
All genders
The mechanisms underlying cystic fibrosis related diabetes (CFRD) pathophysiology must be better defined if care for people with CFRD is to be optimized or if development of CFRD is to be interrupted. Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion …
 Aging Chronobiome Study
18 years - 75 years
Accepts healthy volunteer
All genders
We invite you to participate in a research study where we explore how young and old people differ in their behavioral and biological rhythms. The main criteria to qualify as a research subject are: 1.) you are apparent healthy, 2.) you own a smartphone and 3.) you are either between …
 Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)
18 years - 100 years
All genders
Interventional
The purpose of this study is to find out if a drug called dapagliflozin would be effective in improving the blood tests and symptoms related to your heart failure.
 Mixed Meal Tolerance Test and Cirrhosis Study
1 years - 75 years
All genders
This is a study of 12 subjects with cirrhosis. Blood is collected at CHPS for metabolomic analysis and MMTT. The meal consumed for MMTT will be a convenience-style breakfast. In addition to research testing on blood, urine, and stool, dietary recalls and the Penn Diet Survey will be conducted. The …
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